ID A0A0Q4VBB7_9MICO Unreviewed; 767 AA.
AC A0A0Q4VBB7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=ASF23_03425 {ECO:0000313|EMBL:KQO65175.1};
OS Curtobacterium sp. Leaf261.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Curtobacterium.
OX NCBI_TaxID=1736311 {ECO:0000313|EMBL:KQO65175.1, ECO:0000313|Proteomes:UP000050821};
RN [1] {ECO:0000313|EMBL:KQO65175.1, ECO:0000313|Proteomes:UP000050821}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf261 {ECO:0000313|EMBL:KQO65175.1,
RC ECO:0000313|Proteomes:UP000050821};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQO65175.1, ECO:0000313|Proteomes:UP000050821}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf261 {ECO:0000313|EMBL:KQO65175.1,
RC ECO:0000313|Proteomes:UP000050821};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQO65175.1}.
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DR EMBL; LMMJ01000001; KQO65175.1; -; Genomic_DNA.
DR RefSeq; WP_055948779.1; NZ_LMMJ01000001.1.
DR AlphaFoldDB; A0A0Q4VBB7; -.
DR STRING; 1736311.ASF23_03425; -.
DR OrthoDB; 9787585at2; -.
DR Proteomes; UP000050821; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000050821}.
FT DOMAIN 288..615
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 309..316
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 767 AA; 83489 MW; 3D97949FABDD6BAA CRC64;
MPQISWMNAK QKLEKPTKVK VFNFLEKLQE NDAIPGLHIE PIQNSVDARA RTGRVDGSLR
AVLYRIEVEP GGPLYVYIGT YEHDEGIEIA RTRVLRVNPI NGVTELINAG APEPVRTTTP
FVAESATGPG AGHASSAVAL LVEHGYVVED LTHQLGFDDR TAAALMAVPD EDALLLLGAE
LPNQWQQNAV LGLAVGDSIE TIKTSLGLGA PVAAETSGEA PVDVTVDVDD RDGVRAPATT
LEPTASPDDA LVASLQRPAS RMQFTLIEDN AELRRVIDGG DFGAWRVFLH PEQRAYASRS
YNGPFRLSGG AGTGKTVVLL HRARALEARY PGSRIALTTF TRALSTALDR DVQRLDPSLD
RSRRLGAPGV LSSGVDQLAA AVRDNASKDR WATAMSAVLG HSVEGSVELV SNDHGWLEAI
DDADGGLPEE LATTSFLEAE YLQVILPNRI TTGDEYRSVR RAGRGIALDR ARRNAVWKVV
ERFRANSRSL GRLSWAELSS VAAAHLAAHP SERPIDHLLI DEAQDLTPSQ WQLLRELVPE
GKDDLFIAED AHQRIYGQHV VLSRYGIKIT GRSRRLTLNY RTTQQNLQWA LGVLEGASFE
DSEGTVESAH GYRSARRGPA PELHGAATPA DQFSFVTDRV RSWLDAGVAP ETIAVLVRGK
KQASAVVQQL SAKGVSVSDM DAPRGLPQVM TMHRAKGMEF SRVVMFDVTN GVIPSPWALR
DKTGDDLDDA MLRERSLLYV AASRARDELV VTWRGVRSSL IENVSHL
//
