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Database: UniProt
Entry: A0A0Q5D1N0_9RHIZ
LinkDB: A0A0Q5D1N0_9RHIZ
Original site: A0A0Q5D1N0_9RHIZ 
ID   A0A0Q5D1N0_9RHIZ        Unreviewed;       947 AA.
AC   A0A0Q5D1N0;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   28-MAR-2018, entry version 19.
DE   RecName: Full=Translation initiation factor IF-2 {ECO:0000256|HAMAP-Rule:MF_00100, ECO:0000256|RuleBase:RU000644, ECO:0000256|SAAS:SAAS00048520};
GN   Name=infB {ECO:0000256|HAMAP-Rule:MF_00100};
GN   ORFNames=ASG19_06020 {ECO:0000313|EMBL:KQQ38589.1};
OS   Rhizobium sp. Leaf306.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=1736330 {ECO:0000313|EMBL:KQQ38589.1, ECO:0000313|Proteomes:UP000052122};
RN   [1] {ECO:0000313|EMBL:KQQ38589.1, ECO:0000313|Proteomes:UP000052122}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Leaf306 {ECO:0000313|EMBL:KQQ38589.1,
RC   ECO:0000313|Proteomes:UP000052122};
RA   Millard Andrew;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KQQ38589.1, ECO:0000313|Proteomes:UP000052122}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Leaf306 {ECO:0000313|EMBL:KQQ38589.1,
RC   ECO:0000313|Proteomes:UP000052122};
RA   Vorholt J.;
RT   "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: One of the essential components for the initiation of
CC       protein synthesis. Protects formylmethionyl-tRNA from spontaneous
CC       hydrolysis and promotes its binding to the 30S ribosomal subunits.
CC       Also involved in the hydrolysis of GTP during the formation of the
CC       70S ribosomal complex. {ECO:0000256|HAMAP-Rule:MF_00100,
CC       ECO:0000256|RuleBase:RU000644, ECO:0000256|SAAS:SAAS00320075}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00100,
CC       ECO:0000256|SAAS:SAAS00362982}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. IF-2
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_00100,
CC       ECO:0000256|RuleBase:RU000644, ECO:0000256|SAAS:SAAS00554628}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KQQ38589.1}.
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DR   EMBL; LMNX01000001; KQQ38589.1; -; Genomic_DNA.
DR   RefSeq; WP_062454204.1; NZ_LMNX01000001.1.
DR   EnsemblBacteria; KQQ38589; KQQ38589; ASG19_06020.
DR   Proteomes; UP000052122; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.10050; -; 1.
DR   HAMAP; MF_00100_B; IF_2_B; 1.
DR   InterPro; IPR013575; IF2_assoc_dom_bac.
DR   InterPro; IPR006847; IF2_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR000795; TF_GTP-bd_dom.
DR   InterPro; IPR000178; TF_IF2_bacterial-like.
DR   InterPro; IPR015760; TIF_IF2.
DR   InterPro; IPR023115; TIF_IF2_dom3.
DR   InterPro; IPR036925; TIF_IF2_dom3_sf.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   PANTHER; PTHR43381; PTHR43381; 1.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF11987; IF-2; 1.
DR   Pfam; PF08364; IF2_assoc; 1.
DR   Pfam; PF04760; IF2_N; 1.
DR   SUPFAM; SSF50447; SSF50447; 2.
DR   SUPFAM; SSF52156; SSF52156; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00487; IF-2; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
DR   PROSITE; PS01176; IF2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000052122};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00100,
KW   ECO:0000256|SAAS:SAAS00048564};
KW   GTP-binding {ECO:0000256|HAMAP-Rule:MF_00100,
KW   ECO:0000256|SAAS:SAAS00048516};
KW   Initiation factor {ECO:0000256|HAMAP-Rule:MF_00100,
KW   ECO:0000256|RuleBase:RU000644, ECO:0000256|SAAS:SAAS00440472,
KW   ECO:0000313|EMBL:KQQ38589.1};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00100,
KW   ECO:0000256|SAAS:SAAS00048538};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00100,
KW   ECO:0000256|RuleBase:RU000644, ECO:0000256|SAAS:SAAS00048553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000052122}.
FT   DOMAIN      445    612       Tr-type G. {ECO:0000259|PROSITE:PS51722}.
FT   NP_BIND     454    461       GTP. {ECO:0000256|HAMAP-Rule:MF_00100}.
FT   NP_BIND     500    504       GTP. {ECO:0000256|HAMAP-Rule:MF_00100}.
FT   NP_BIND     554    557       GTP. {ECO:0000256|HAMAP-Rule:MF_00100}.
FT   REGION      448    596       G-domain. {ECO:0000256|HAMAP-Rule:
FT                                MF_00100}.
FT   COILED      193    234       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   947 AA;  101944 MW;  F08B1123325EA43C CRC64;
     MTDNNDDKTL GVKKTLTLKP SGVTQGTVRQ DMGRGRTKAV VVETVKRRPT RPLDEKPITP
     IAAPAPRPVE AAAPIAPRPQ PATPAAPAPA APVAAAAPAA PAPAAPVSQP SPPQPRVQQP
     SSQGYRPGSS QGQRPSSSQG QRPSSHQGQR PQQPSQPQRQ PQRSGGAVLH DLSASEMDAR
     RRALVEAQAR DVVEAKQRVE DDARRKVEDE RRKVEEAAEA ARLAEEAKAR AAEEALRPAP
     VAPAPAAADR NANTQDNRNS ARPTPGAAPV AAPVIGRGRR NDEEEDRAPA RTIPGRGRVA
     APVPAKPPTR PKVEEGRRQG KLTITAASTD DDGTGRGRSM AAMRRRQEKF RRSQMQETRE
     KVMREVILPE TITIQELSQR MSERAVDVIK YLMKEGQMMK AGDVIDADLA EIIAGEFGHT
     VKRVSESDVE EGIFNQMDDA GEMVSRPPVV TIMGHVDHGK TSLLDAIRQA NVVSGEAGGI
     TQHIGAYQVE QNGQKITFID TPGHAAFTAM RARGAQATDI AILVVAADDS VMPQTIESIS
     HAKAAGVPII VAINKIDKHE ANPDKVRQQL LQHEVFVESL GGEVLDVEVS AKNKTNLDKL
     LEAVLLQAEI LDLKADPVRT AEGIVIEAQL DRGRGAVATV LVQKGTLKPG QIIVAGDQWG
     RVRALVTDKG VHVKEAGPAM PVEVLGLSST PAAGDKFAVV ENESRAREIS EYRQRLARDK
     AVARQSGQRG SLEQMMSKLQ NTGYKEFPLL IKGDVQGSVE AIIGALDKLG TDEVRARIVH
     SGAGAITESD LALAESSEAA IIGFNVRANA QARIAADRAG TEIRYYNIIY DLVDDVKAAM
     SGLLSPERRE TFLGNAEILE VFNITKTGKV AGCRVVEGKV ERGAGVRLLR DNVVIHEGKL
     KTLKRFKDEV GEVPMGQECG MAFENYEDIR AGDTIECFRV EHITRTL
//
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