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Database: UniProt
Entry: A0A0Q5EKR8_9RHIZ
LinkDB: A0A0Q5EKR8_9RHIZ
Original site: A0A0Q5EKR8_9RHIZ 
ID   A0A0Q5EKR8_9RHIZ        Unreviewed;       522 AA.
AC   A0A0Q5EKR8;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   16-JAN-2019, entry version 25.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=ASF69_16995 {ECO:0000313|EMBL:KQQ56635.1};
OS   Rhizobium sp. Leaf311.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=1736332 {ECO:0000313|EMBL:KQQ56635.1, ECO:0000313|Proteomes:UP000052165};
RN   [1] {ECO:0000313|EMBL:KQQ56635.1, ECO:0000313|Proteomes:UP000052165}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Leaf311 {ECO:0000313|EMBL:KQQ56635.1,
RC   ECO:0000313|Proteomes:UP000052165};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KQQ56635.1, ECO:0000313|Proteomes:UP000052165}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Leaf311 {ECO:0000313|EMBL:KQQ56635.1,
RC   ECO:0000313|Proteomes:UP000052165};
RA   Vorholt J.;
RT   "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KQQ56635.1}.
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DR   EMBL; LMNZ01000007; KQQ56635.1; -; Genomic_DNA.
DR   RefSeq; WP_062587694.1; NZ_LMNZ01000007.1.
DR   EnsemblBacteria; KQQ56635; KQQ56635; ASF69_16995.
DR   Proteomes; UP000052165; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000052165};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      212    343       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      427    496       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     220    227       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   522 AA;  58094 MW;  3723F862ADF49940 CRC64;
     MQLNLVMGAV ANGDRTPKAC DAAGTDAAGD KQDMKHDALF ERFSARLKAQ VGPEVYASWF
     ARLKLHSVSK SVVRFTVPTT FLKSWINNRY IDLITTLIQS EDADVLKVEI LVRSASRPVR
     PAQVEERALP APDMSTAAQR AKPFIPPQPM SSAQPSGMSP SAPVTRHSGS GPFFGSPLDS
     RFTFDTFVEG SSNRVALAAA KTIAEAGAGA VRFNPLFIHA GVGLGKTHLL QAIANAAIDS
     PRNPRVVYLT AEYFMWRFAT AIRDNDALTL KDTLRNIDLL VIDDMQFLQG KMIQHEFCHL
     LNMLLDSAKQ VVVAADRAPW ELESLDPRVR SRLQGGMAIE IEGPDYEMRY EMLTQRIAAA
     RQEDPSFDIP EEIVSHVARS VTASGRELEG AFNQLIFRRS FEPNLSVERV DELLAHLVGT
     GEAKRVRIED IQRIVARHYN VSRQELVSNR RTRVIVKPRQ VAMYLAKMLT PRSFPEIGRR
     FGGRDHTTVL HAVRKIEELI GGDSKLGHEV ELLKRLINEN NA
//
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