ID A0A0Q5HXD5_9BURK Unreviewed; 959 AA.
AC A0A0Q5HXD5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASF77_04600 {ECO:0000313|EMBL:KQQ97238.1};
OS Massilia sp. Leaf139.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Telluria group; Massilia.
OX NCBI_TaxID=1736272 {ECO:0000313|EMBL:KQQ97238.1, ECO:0000313|Proteomes:UP000051760};
RN [1] {ECO:0000313|EMBL:KQQ97238.1, ECO:0000313|Proteomes:UP000051760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf139 {ECO:0000313|EMBL:KQQ97238.1,
RC ECO:0000313|Proteomes:UP000051760};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQQ97238.1, ECO:0000313|Proteomes:UP000051760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf139 {ECO:0000313|EMBL:KQQ97238.1,
RC ECO:0000313|Proteomes:UP000051760};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQQ97238.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LMOJ01000001; KQQ97238.1; -; Genomic_DNA.
DR RefSeq; WP_056335044.1; NZ_LMOJ01000001.1.
DR AlphaFoldDB; A0A0Q5HXD5; -.
DR STRING; 1736272.ASF77_04600; -.
DR OrthoDB; 5571399at2; -.
DR Proteomes; UP000051760; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 4.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF13188; PAS_8; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000051760};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 302..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 322..375
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 405..476
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 483..533
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 820..953
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 959 AA; 104905 MW; 82A3FC6BA05DF0C8 CRC64;
MLSSFRSGRL ALAPALAAVS AAIVLLMTLI TLQLVGQTLA KQAEADIGQT LAELAFQTTD
KLDRGMYERY REVKLMAERH GITDPAVPVE VKRAALQSMQ STHPYYAWIG MTDNRGTVRI
ATGGLLEGKD VSSRPWFAAA YEGVHLHDVH EAVLLAKLLP NPTREPKRFF DIAFPYRGPD
GVIQGIFGTH LSWQWAAAVE RSVLRPLAAR ESVDTLILSR NGVVLLGPKD YADKQLNQES
FRRALRGGND SVIETWPDGR RYLVGYSRSV GHESYPGLGW VVVVRQPLER AFAPVAELRE
QILWAGLCAA AIVSLLVWAF ARDLARPLQT LARQADALRS GDARTLPPLS SRLTEVQILR
SAFDALLSKL LANEQGLREL NAGLEARVGE RTAELHRAIE ETRKGESRVK AIIDTALDAF
VGIDSDNRIT DWNPRAEEIF GWTRAEVLGR TVSETIIPQR FRQAHEAGMR RFAASGSSGV
VGQRIQLSAL RRIGEEFPVE MTIGQIHAGE ASFFGAFIQD ISERKRIEDE LARERELLGA
VLDSIDVGVV VCSSAGEITL FNRAARDIHG LPPAPLAPED WGGHYRLFDA DGETPLSAEQ
IPLFRALHGQ LVENSELTVK PLDAPPRFLF ASGRALHAAD GTGIGAVIAL KDVTALKESA
RRLEASERSL RTITNNLPVL IGHVGRDERY RFANATYASW FKVPPEEIVG CSIEEVMGGA
LYREHAPVLE RSLAGETVRF EVELPMDDGM RTVEITRIPD IHDGVYNGFY VLGADVTAAR
RHEEELSRLA RVDTLTGLPN RRAYHEHLEA ALQRARRAGS GVALMFLDVD RFKQVNDTLG
HAAGDAVLHE FAGRVRGAVR ATDTVCRLAG DEFTVILEGL KSPGEAALVA AKILKAFEAP
FLLESGARTV STSIGVAYAD VHPADTALLG AEADKALYQA KSAGRARFAV SRLEAVPVC
//
