ID A0A0Q5JXK3_9MICO Unreviewed; 1095 AA.
AC A0A0Q5JXK3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=ASF76_04615 {ECO:0000313|EMBL:KQR24956.1};
OS Microbacterium sp. Leaf151.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=1736276 {ECO:0000313|EMBL:KQR24956.1, ECO:0000313|Proteomes:UP000051582};
RN [1] {ECO:0000313|EMBL:KQR24956.1, ECO:0000313|Proteomes:UP000051582}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf151 {ECO:0000313|EMBL:KQR24956.1,
RC ECO:0000313|Proteomes:UP000051582};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQR24956.1, ECO:0000313|Proteomes:UP000051582}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf151 {ECO:0000313|EMBL:KQR24956.1,
RC ECO:0000313|Proteomes:UP000051582};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQR24956.1}.
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DR EMBL; LMOR01000002; KQR24956.1; -; Genomic_DNA.
DR RefSeq; WP_055953723.1; NZ_LMOR01000002.1.
DR AlphaFoldDB; A0A0Q5JXK3; -.
DR STRING; 1736276.ASF76_04615; -.
DR OrthoDB; 4812256at2; -.
DR Proteomes; UP000051582; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF55; DNA HELICASE; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 17..395
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 396..714
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 38..45
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1095 AA; 118949 MW; 8C60FCF88597680D CRC64;
MTGGLSAATI AAALGLFPPT AEQTAVIEAP LAPALVVAGA GSGKTETMAG RVVWLVANAH
VRRDEVLGLT FTRKAAGELA ERIQRRLQRL SEFESRGLLP ALPALHAAGR LSVFGDLAQV
EGARGDAARR EALDALASEV GVSAVSASDA DQLLHRPTVS TYNSFADSIV REHGLRIGRD
AESAVLSESA AWLLMRRVVF TSDDPRLEER QESPRTLIDA ALRIARDGVD NLVDLDRLAA
FPDEFGRVVE RPSTSNRVDV YKEVADAATK VSALSLLADL AAAYDREKAR LGVMDFADQV
AGALRIAQEH PAVVEELRAR YRVVLLDEYQ DTSVVQTDLL ATLFGGTGVM AVGDPHQAIY
AWRGASAGNL GGFPAAFAPA CESQHFSLLT SWRNSARVLD AANAVLAPLA ARAAVAVEEL
RSRPGAPDGV VETVFENDLD AEADRVASWF VGVRAARAAE GRLTTGALLF RSKKHMVRFG
DALGRRGIPH RILGLGGLLT TPEVVDVVSV LRVMSDPEAG SALIRLLSGP RWAVGLADLR
ALAQVARRLA THDVALQPLA ADVVNRLRST PGADRASLVD ALDFVTRQTD GHGWLADITP
EGRARLREAG AVFAGLRRSA GAPIPELIRL IETELRLDIE LAANESRGPA RIASAQLRAF
VDEIRGFLAA DESGSVASLL AWLDHAEQAD EFAPRTEPPE ADVVQLLTIH GSKGLEWDAV
AVVRLVTDEL PSLARDTKGW LGFGILPSEF RGDSAWLPVF GWRGAETQQD LKAAIEAFVS
DNRARQLDED RRLAYVAFTR ARDHLLLSGS SWSGTKRPRR PSVFLEEAAE ALGIDLAVGE
LGDDPYDGER RLLHWPLDPL GARRTAITAA VATATAARAN PPARADDDLE LLLAERADRL
RPTHAPAPTR IPASKFKDFV ADYGRAVDDL RRPMPERPYR QTRLGTLFHA WVEQRSGHVG
AGIGLDDDGL WDDDEIGASS ADAADLQRLR ECFERSEWAN LRPLEVETEI DFVTTRLDGR
EHVVICKLDA VYRRGDRYEI VDWKTGRPPT TDADRRARML QLELYREAYH AKHGIDIDLI
DVTLFYVGDE LVLRS
//
