ID A0A0Q5UXM0_9SPHN Unreviewed; 791 AA.
AC A0A0Q5UXM0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=ASG20_08095 {ECO:0000313|EMBL:KQS49030.1};
OS Sphingomonas sp. Leaf198.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1736299 {ECO:0000313|EMBL:KQS49030.1, ECO:0000313|Proteomes:UP000050871};
RN [1] {ECO:0000313|Proteomes:UP000050871}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf198 {ECO:0000313|Proteomes:UP000050871};
RA Garrido-Oter R.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000050871}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf198 {ECO:0000313|Proteomes:UP000050871};
RA Vorholt J.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQS49030.1}.
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DR EMBL; LMPX01000002; KQS49030.1; -; Genomic_DNA.
DR RefSeq; WP_056050907.1; NZ_LMPX01000002.1.
DR AlphaFoldDB; A0A0Q5UXM0; -.
DR STRING; 1736299.ASG20_08095; -.
DR OrthoDB; 9796100at2; -.
DR Proteomes; UP000050871; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17536; REC_YesN-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KQS49030.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000050871};
KW Transferase {ECO:0000313|EMBL:KQS49030.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 422..650
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 674..788
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 724
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 791 AA; 84204 MW; B3744408BC811BB6 CRC64;
MASLALPTPA RNAALVAIAS GVVAAAIVLL LVGSWIVAAG FFAAAAIVIG ALIAWRLLNP
VAKDAPRPVD WDLTRTVAEA GTDAIAITDR AGRLVCANDA YDALFAGFPT PPGLPLDDVG
TAALADAGRT AWRDGIARVE RLNARGICLS AHIARAGDEA DMLVWRFVTA QDHDLAETLA
ALLPGPTGDR LGGSGIMAAL LSTDGRVRTA NRVLRARASG NDHESIDGRD FASFLITDSR
GFVRFEREGL EGTPLRVLQV PFLEGDDAPV LVALLDDEEA APPVGASAAA HVRSLVSLMP
FGMALVDRDG RFLQMNTSFL RAAGVNPVAP PLYPGDLVVR EDKAAVADAI RKFANGATHS
ADMAVRLKDH PDEPVALTIA GARGLGDAAV LLSLKDNSEE SRLKREVAQA TKMQAVGQLA
GGVAHDFNNI LTAIIGHCDL MLMRHSPGDS DYDDIQQVRT NSNRAASLTR QLLAFSRQQT
LRPQILQLPD VVSEVSNLLK RLMGENVRLD MTHGRNLGPV RADPGQLEQV VVNLAVNARD
AIVSANARGG GVLTITTRAV YASEVRAMAS DILPVADYTA LIVQDTGTGI PPDVLPKIFE
PFFTTKEFGR GTGLGLSTVY GIVKQSGGYI FADSKLGQGA TFTMYLPVHS APAATRPAIV
KPAPKPVDLW GTGTILLVED EDMVRAVAER ALSRQGYTVL TAENGEVALE VLEKHGRPDL
LISDVVMPQM DGPTMVRHVR EKYPDLPILF MSGYAEEQLR KSIDLDNVSF LPKPFSVQEL
AEAARDVLAT R
//
