ID A0A0Q6A6G3_9FLAO Unreviewed; 376 AA.
AC A0A0Q6A6G3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=3-hydroxybutyryl-CoA dehydrogenase {ECO:0000313|EMBL:KQT20634.1};
GN ORFNames=ASG22_16810 {ECO:0000313|EMBL:KQT20634.1};
OS Chryseobacterium sp. Leaf405.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=1736367 {ECO:0000313|EMBL:KQT20634.1, ECO:0000313|Proteomes:UP000051197};
RN [1] {ECO:0000313|EMBL:KQT20634.1, ECO:0000313|Proteomes:UP000051197}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf405 {ECO:0000313|EMBL:KQT20634.1,
RC ECO:0000313|Proteomes:UP000051197};
RX PubMed=26633631; DOI=.1038/nature16192;
RA Bai Y., Muller D.B., Srinivas G., Garrido-Oter R., Potthoff E., Rott M.,
RA Dombrowski N., Munch P.C., Spaepen S., Remus-Emsermann M., Huttel B.,
RA McHardy A.C., Vorholt J.A., Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiota.";
RL Nature 528:364-369(2015).
RN [2] {ECO:0000313|Proteomes:UP000051197}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf405 {ECO:0000313|Proteomes:UP000051197};
RA Garrido-Oter R., Mueller D.B.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000051197}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf405 {ECO:0000313|Proteomes:UP000051197};
RA Vorholt J.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQT20634.1}.
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DR EMBL; LMQN01000021; KQT20634.1; -; Genomic_DNA.
DR RefSeq; WP_055988521.1; NZ_LMQN01000021.1.
DR AlphaFoldDB; A0A0Q6A6G3; -.
DR STRING; 1736367.ASG22_16810; -.
DR OrthoDB; 9771883at2; -.
DR Proteomes; UP000051197; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 1.10.1040.50; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR48075:SF5; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR Pfam; PF00725; 3HCDH; 2.
DR Pfam; PF02737; 3HCDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 2..180
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 183..280
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
FT DOMAIN 302..376
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
FT COILED 40..67
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 376 AA; 42103 MW; 36C4D0F145E30C4A CRC64;
MNVGIIGAGT MGVGIAQVAA TAGCKVVLFD ANTSQIDKAL SGLEKTLNKL VEKAKISQEK
ATEIKNNIIK GETLQDLKDS DLVIEAIIEN KEIKTKVFTE LEKYVSESCV IASNTSSISI
TSLGAELQKP ERFIGIHFFN PAPLMPLVEI IPSLLTEKSL AEKIYTLMKG WGKTPVIAKD
IPGFIVNRIA RPYYGEGLRI VEENIATVEQ VDDAMKTIGN FKMGPFELMD LIGVDVNFSV
TKTVYNEYFY DPKYKPSLFQ QRMSEAKLHG RKTGKGFYDY SEGVEKPVAE KDDALYQQIF
LRIISMLINE AVEAKRIDIA NDEDLELAMQ KGVNYPKGLL AWGKEIGYAK ISETLQNLYE
EYQEERYRQS PLLRKL
//
