ID   A0A0Q6B662_9PROT        Unreviewed;       289 AA.
AC   A0A0Q6B662;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:KQT37381.1};
GN   ORFNames=ASG34_13565 {ECO:0000313|EMBL:KQT37381.1};
OS   Methylophilus sp. Leaf416.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC   Methylophilaceae; Methylophilus.
OX   NCBI_TaxID=1736373 {ECO:0000313|EMBL:KQT37381.1, ECO:0000313|Proteomes:UP000050891};
RN   [1] {ECO:0000313|EMBL:KQT37381.1, ECO:0000313|Proteomes:UP000050891}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Leaf416 {ECO:0000313|EMBL:KQT37381.1,
RC   ECO:0000313|Proteomes:UP000050891};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KQT37381.1, ECO:0000313|Proteomes:UP000050891}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Leaf416 {ECO:0000313|EMBL:KQT37381.1,
RC   ECO:0000313|Proteomes:UP000050891};
RA   Schulze-Lefert P.;
RT   "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KQT37381.1}.
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DR   EMBL; LMQS01000005; KQT37381.1; -; Genomic_DNA.
DR   RefSeq; WP_055831400.1; NZ_LMQS01000005.1.
DR   AlphaFoldDB; A0A0Q6B662; -.
DR   OrthoDB; 9809920at2; -.
DR   Proteomes; UP000050891; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          3..289
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   289 AA;  30928 MW;  0FB077CE9A3767E9 CRC64;
     MFKKIVIFGV GLIGGSVALA LKKLPNPPHI TGVGRSNQSL QEALSLGLID SAETDIAIAL
     ENADLILIAT PVAQTPAILK SILPHLAAQT VITDAGSTKS DVMAYAEAEL GEQFKQFVGG
     HPIAGAEKSG PAAAMADLYI GKNVILTPGL VTDPEAVLKV TELWKVCGAL VSNMRPEEHD
     SVFAAVSHLP HLLAFALVED LAKRDNAELL FKFAASGFRD FTRIAGSHPE MWRDIALANK
     QALLQELNTY QQAIGEMTAL LENNDHKGLF ALFEHASHAR NAWAKSKIQ
//