ID A0A0Q6BDD4_9PROT Unreviewed; 802 AA.
AC A0A0Q6BDD4;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0000313|EMBL:KQT43741.1};
GN ORFNames=ASG34_02885 {ECO:0000313|EMBL:KQT43741.1};
OS Methylophilus sp. Leaf416.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Methylophilaceae; Methylophilus.
OX NCBI_TaxID=1736373 {ECO:0000313|EMBL:KQT43741.1, ECO:0000313|Proteomes:UP000050891};
RN [1] {ECO:0000313|EMBL:KQT43741.1, ECO:0000313|Proteomes:UP000050891}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf416 {ECO:0000313|EMBL:KQT43741.1,
RC ECO:0000313|Proteomes:UP000050891};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQT43741.1, ECO:0000313|Proteomes:UP000050891}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf416 {ECO:0000313|EMBL:KQT43741.1,
RC ECO:0000313|Proteomes:UP000050891};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQT43741.1}.
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DR EMBL; LMQS01000001; KQT43741.1; -; Genomic_DNA.
DR RefSeq; WP_055826247.1; NZ_LMQS01000001.1.
DR AlphaFoldDB; A0A0Q6BDD4; -.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000050891; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 482..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 512..531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..199
FT /note="DUF4131"
FT /evidence="ECO:0000259|Pfam:PF13567"
FT DOMAIN 245..509
FT /note="ComEC/Rec2-related protein"
FT /evidence="ECO:0000259|Pfam:PF03772"
FT DOMAIN 542..608
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF00753"
SQ SEQUENCE 802 AA; 88852 MW; 9E677AE65B1F805C CRC64;
MLPGATVGLL FGVWLFQQQP HLWSVSAWLG WLAALILIGC LAYGNQVIAA RHIPYQHTFR
KLFIIVLIAA LGFAWAQLLA WDRLQTQLPS DCEQQVIAVQ GVIVSVPERD ARGQHVDFAV
ERSFTADCPM PKRVRLHLYH QSYRGESAKA SPVLPILQAG ERWQWSVRLK RPHATRNPHG
FDYAAWCLSN NIGASGAIVS KTPMLRLQRL VWKPSALIAH WRAAVGNRIE KVLGTTPQSA
VLRALVIGDD SQIARADWQL FVDTGINHLI SISGLHITML ASMGYLLTGW AWRLRPRLAL
RIPSRLAAGV GGALVAIAYS ALAGFSIPTE RTLLMLLTMI VMLSLKQRLP FSWVLSAAVW
VVLVVDPWAV MAPGFWLSFG AVTILAFAMS GRLRPARWWQ SALQTQWVIT LAFVPVLILL
FNQLSLISPL ANGLAIPIVS LAIVPLAIDG AILPLDFLLH LSATLWEWCA HGLHWLRQLP
GAVCYLSTPP IWAWLLAMAG MLVWLMPRGW PLRWAGLLLW LPLLLPTQVA LQPGQMRVTV
LDVGQGLSVL VQTAHHTMLY DAGPAYNEES DAGQRIVLPY LRHLGVSHLD AVVISHDDND
HSGGMASVLA GVSVDNFLSS LTPASDFFKQ IQTLPNPPVL RPQPCYQGQQ WQWDNISFRM
LSPEKNTDTD LKDNDKSCVL QVQSPHGSLL LTGDIEKEAE RRLLASEPDQ LATTVMTMPH
HGSKTSSTIG FVNATKPAIA IATVGYLNRF GHPKPEVISR YQAIETTVLR SDNDGAILID
FLSGEAPVVK RWRQIEPHYW EL
//
