ID A0A0Q6PRG7_9MICO Unreviewed; 711 AA.
AC A0A0Q6PRG7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Radical SAM protein {ECO:0000313|EMBL:KQV06143.1};
GN ORFNames=ASC63_01240 {ECO:0000313|EMBL:KQV06143.1};
OS Leifsonia sp. Root112D2.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Leifsonia.
OX NCBI_TaxID=1736426 {ECO:0000313|EMBL:KQV06143.1, ECO:0000313|Proteomes:UP000051914};
RN [1] {ECO:0000313|EMBL:KQV06143.1, ECO:0000313|Proteomes:UP000051914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root112D2 {ECO:0000313|EMBL:KQV06143.1,
RC ECO:0000313|Proteomes:UP000051914};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQV06143.1, ECO:0000313|Proteomes:UP000051914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root112D2 {ECO:0000313|EMBL:KQV06143.1,
RC ECO:0000313|Proteomes:UP000051914};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQV06143.1}.
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DR EMBL; LMCU01000001; KQV06143.1; -; Genomic_DNA.
DR RefSeq; WP_055808959.1; NZ_LMCU01000001.1.
DR AlphaFoldDB; A0A0Q6PRG7; -.
DR STRING; 1736426.ASC63_01240; -.
DR OrthoDB; 9785699at2; -.
DR Proteomes; UP000051914; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR CDD; cd00081; Hint; 1.
DR Gene3D; 3.80.30.30; -; 1.
DR Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 1.
DR Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR InterPro; IPR003586; Hint_dom_C.
DR InterPro; IPR003587; Hint_dom_N.
DR InterPro; IPR036844; Hint_dom_sf.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR006142; INTEIN.
DR InterPro; IPR030934; Intein_C.
DR InterPro; IPR004042; Intein_endonuc.
DR InterPro; IPR006141; Intein_N.
DR InterPro; IPR004860; LAGLIDADG_2.
DR InterPro; IPR040086; MJ0683-like.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; NF038135; rSAM_Rv2578c; 1.
DR NCBIfam; NF038136; rSAM_Rv_intein; 1.
DR PANTHER; PTHR43432; SLR0285 PROTEIN; 1.
DR PANTHER; PTHR43432:SF3; SLR0285 PROTEIN; 1.
DR Pfam; PF14528; LAGLIDADG_3; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR PRINTS; PR00379; INTEIN.
DR SMART; SM00305; HintC; 1.
DR SMART; SM00306; HintN; 1.
DR SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR SUPFAM; SSF55608; Homing endonucleases; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS50818; INTEIN_C_TER; 1.
DR PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
DR PROSITE; PS50817; INTEIN_N_TER; 1.
PE 4: Predicted;
KW Autocatalytic cleavage {ECO:0000256|ARBA:ARBA00022813};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protein splicing {ECO:0000256|ARBA:ARBA00023000};
KW Reference proteome {ECO:0000313|Proteomes:UP000051914}.
FT DOMAIN 210..347
FT /note="DOD-type homing endonuclease"
FT /evidence="ECO:0000259|PROSITE:PS50819"
FT DOMAIN 412..433
FT /note="Intein C-terminal splicing"
FT /evidence="ECO:0000259|PROSITE:PS50818"
SQ SEQUENCE 711 AA; 78623 MW; 196EE54D2546B361 CRC64;
MRWSGQELGE EQQNALPGLA RLNNLVRSVR TPEFAGITFH EVLAKSALNK VPGTGKNANK
SKASALPFGW TINPYRGCSH ACAYCADPET LVLMGDGRQK PLWMVEVGEE IYGTEVRGNY
RRYVKTTVLA SWNTRKRAYR TTLADGTELI TSGDHRLLTE RGWKHVQGTM SGAHQRPYLT
PNNKLMGFGL NGLTNIQHAQ FNADYRRGYL TGMIRGDGML FRKDYRRANG GVNHLSSFRL
ALADVEALNR SRVYLEAEGI RTTTRPFAVA SATRRPMQAI HTAKRAHYDR ISELIRWPAQ
RSDDWNAGYL AGIFDAEGSC SRGVLRISNK AADVLEQIQS AMTALGIDHV LEPAHPNGVR
NVRVSGGLPM RTRFFTLVGP AITRKLDIEG AAVKSEAKLQ IVSIEDLGET IDMMDITTGT
GDFIANGVIS HNCFARPTHT YLDLDAGKDF DNEIIVKVNV AEVLQRELAK PSWGRHPVAL
GTNTDPYQRA EGRYALMPGI IDALADSGTP FSILTKGSLL RRDLDRIADA ATRVPVDLAM
SIAIYDDELQ HSIEPGTPST SARLATVTAV REHGLNCSVF LMPIIPYLTD SKAHLDEALR
RIEEAGATSV LYTAMHLRPG VKEWFMLWLE REHPELVARY SEMYGAGAYP PKEYRAWLSA
RIRPLIARHG LTRGQEDPVT GGVRTVRAGR PRFTAPVPDS AGTLEIAPTL F
//
