ID A0A0Q6WPX6_9BURK Unreviewed; 1887 AA.
AC A0A0Q6WPX6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=ASC87_06775 {ECO:0000313|EMBL:KQV91770.1};
OS Rhizobacter sp. Root1221.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales; Rhizobacter.
OX NCBI_TaxID=1736433 {ECO:0000313|EMBL:KQV91770.1, ECO:0000313|Proteomes:UP000051465};
RN [1] {ECO:0000313|EMBL:KQV91770.1, ECO:0000313|Proteomes:UP000051465}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root1221 {ECO:0000313|EMBL:KQV91770.1,
RC ECO:0000313|Proteomes:UP000051465};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQV91770.1, ECO:0000313|Proteomes:UP000051465}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root1221 {ECO:0000313|EMBL:KQV91770.1,
RC ECO:0000313|Proteomes:UP000051465};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQV91770.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LMDI01000034; KQV91770.1; -; Genomic_DNA.
DR RefSeq; WP_056667592.1; NZ_LMDI01000034.1.
DR STRING; 1736433.ASC87_06775; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000051465; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR Gene3D; 3.30.190.20; -; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 3.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 2.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 2.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 3.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000051465};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SOS response {ECO:0000256|ARBA:ARBA00023236};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 291..606
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1180..1523
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1310..1333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1310..1330
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1887 AA; 206643 MW; 740643871BBAF09E CRC64;
MSSGLIRIRG ARQHNLKNLD LDIRTGDMTV VTGPSGSGKS SLVFDTLYAE GQRRYVETFS
AYARQFLDRM DRPAVDRVDG VPPAIAIDQT NPVRTSRSTV GTMTELNDHL KLLYARAAEL
YDRETAQLVR HDTPETIYEE LMARTADGDP RLAVTFPVEL PATTTAEEVT QWLSASGFTR
VQAEREIASP TGPRKLLDVV ADRFRLQGTE KVRAIEAIEM ALKRGSGRVN VYVLADEGEP
VLWRYSTGLH CPESDLRYTD PQPALFSFNS AMGACETCRG FGRVIGVDWG LVIPDPKKTL
RGGAVKTLQT PAWQENQEDL MRYAGEAGIP RDTPWSQLTD AQKDWVIQGS PQWSGKWNKQ
WYGVARFFEY LESKAYKMHI RVLLSKYRSY TTCPTCAGAR LKTESLLWRL GSKADADAAL
PPAKRFLPQG VKWNRTQVEA LPGLTVHDLM LVPIERIQRF FANIVLPSSM LDDALKLLLD
EIRTRLKYLN DVGIGYLTLD RQSRTLSGGE VQRINLTTAL GTSLVNTMFV LDEPSIGLHP
RDMNRIVEAM HRLRDAGNTL VVVEHDPAVM LAADRLIDMG PGPGERGGNI VFDGTPAAIR
HADTLTGAYL GARKQVGMGI RRLVTDATAK LILQGARDHN LKDVTVEFPL QHLVCVTGVS
GSGKSTLMQD VLFPALQRHF GKATETPGEH DALLGADWLS DSVFVDQSPI GKTARSNPAS
YVGAFDEIRK LFSQAPLAQQ RGYGAGMFSF NAGDGRCPTC GGSGFEHVEM QFLSDVYLRC
PDCDGKRFRA ELLEVKIDRR LPGDLVRELN VADVLELTVS EAVQLFANDR EVLRVLQPII
DVGLEYVKLG QPVPTLSGGE AQRLKLAGFL AEAAQGATAS RQAVARKGTL FLFDEPTTGL
HFDDIAKLMR AFRKLLDAGH SLVVIEHNLD VIRASDWLID LGPEGGDAGG FVVCTGTPED
VKQHPTSHTG RALADYDRQM GLNGHVVEEG RPLQQVIRGN RDHGDSIRIV NAREHNLKSL
DVDIPRGKFS VVTGVSGSGK STLAFDILFN EGQRRYLESL NAYARSIVQP AGRPEVDAVY
GIPPTVAIEQ RLSRGGRKST VATTTEVWHF LRLLYVKLGI QHCIHDGAPV MPQSAESIAA
QLLRQHKGQH VGLLAPLVIN RKGLYTDLAK WAKARGYTHL RVDGEFVKVE PWPKLDRFKE
HTVELPVGDL VVDAGNEAEL RSLLAKALDL GKGVMHLLSP LNALRGAMLA GTPTRKIGEV
KVFSTKRACP VCATSYPELD PRMFSYNSKH GWCGTCVGTG LALTREQRKA FDDSVRDDDN
KGREQSFPSE EPEVDGVVDE ACPDCGGTRL NAISRAVKFE DHSIAWIAQW SVADCRKWVE
SLALAGRDAE IARDVVSEIR SRLEFLEEVG LGYLTLDRAA PTLSGGEAQR IRLAAQLGSN
LQGVCYVLDE PTIGLHPRDN QILLDALHKL GEKGNTLVVV EHDEDTIRRA DHIIDIGPGA
GKRGGTLVAQ GSVSELASHP DSVTGRSLAH PLVHPIQQRR QMADGPVLTV SNAALHNLQD
VTVDVPLKRL VAVTGVSGSG KSTLARDVLL ANLTFINQRG AKPKWSGCSG IEGWQQIDRV
LEVDQTPIGK TPRSCPATYI GFWDTIRKLF ADTLESRARG YAPNRFSFNT GEGRCPACEG
QGMRTIEMSF LPDVKVPCDV CHGQRFNAET LAVTWRGKSI GDVLRMEVDE AVEFFASMPS
IAHPLQLLKD VGLGYLTLGQ PSPTLSGGEA QRIKLVSELT KVRDEVGRRG QKAPHTLYVL
DEPTVGLHMA DVEKLIRVLH RLVDGGHSVV VIEHDLDVVA EADWIIDLGP EGGVKGGAVV
AECVPEALAL DVRSHTGAAL KPVLARV
//
