ID A0A0Q6Z6Y8_9BRAD Unreviewed; 586 AA.
AC A0A0Q6Z6Y8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Arsenical pump-driving ATPase {ECO:0000256|PIRNR:PIRNR001327};
DE EC=7.3.2.7 {ECO:0000256|PIRNR:PIRNR001327};
GN ORFNames=ASC80_00055 {ECO:0000313|EMBL:KQW21851.1};
OS Afipia sp. Root123D2.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Nitrobacteraceae; Afipia.
OX NCBI_TaxID=1736436 {ECO:0000313|EMBL:KQW21851.1, ECO:0000313|Proteomes:UP000051348};
RN [1] {ECO:0000313|EMBL:KQW21851.1, ECO:0000313|Proteomes:UP000051348}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root123D2 {ECO:0000313|EMBL:KQW21851.1,
RC ECO:0000313|Proteomes:UP000051348};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQW21851.1, ECO:0000313|Proteomes:UP000051348}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root123D2 {ECO:0000313|EMBL:KQW21851.1,
RC ECO:0000313|Proteomes:UP000051348};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Anion-transporting ATPase. {ECO:0000256|PIRNR:PIRNR001327}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=arsenite(in) + ATP + H2O = ADP + arsenite(out) + H(+) +
CC phosphate; Xref=Rhea:RHEA:11348, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:29242, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.7;
CC Evidence={ECO:0000256|PIRNR:PIRNR001327};
CC -!- SIMILARITY: Belongs to the arsA ATPase family.
CC {ECO:0000256|ARBA:ARBA00011040, ECO:0000256|PIRNR:PIRNR001327}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQW21851.1}.
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DR EMBL; LMDP01000001; KQW21851.1; -; Genomic_DNA.
DR RefSeq; WP_056291616.1; NZ_LMDP01000001.1.
DR AlphaFoldDB; A0A0Q6Z6Y8; -.
DR STRING; 1736436.ASC80_00055; -.
DR OrthoDB; 9780677at2; -.
DR Proteomes; UP000051348; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0015446; F:ATPase-coupled arsenite transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR CDD; cd02035; ArsA; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR025723; Anion-transp_ATPase-like_dom.
DR InterPro; IPR027541; Ars_ATPase.
DR InterPro; IPR016300; ATPase_ArsA/GET3.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR04291; arsen_driv_ArsA; 1.
DR NCBIfam; TIGR00345; GET3_arsA_TRC40; 1.
DR PANTHER; PTHR10803; ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE; 1.
DR PANTHER; PTHR10803:SF3; ATPASE GET3; 1.
DR Pfam; PF02374; ArsA_ATPase; 2.
DR PIRSF; PIRSF001327; Arsenical_pump-driving_ATPase; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW Arsenical resistance {ECO:0000256|PIRNR:PIRNR001327};
KW ATP-binding {ECO:0000256|PIRNR:PIRNR001327};
KW Nucleotide-binding {ECO:0000256|PIRNR:PIRNR001327};
KW Reference proteome {ECO:0000313|Proteomes:UP000051348};
KW Translocase {ECO:0000256|PIRNR:PIRNR001327}.
FT DOMAIN 10..229
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 328..527
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 586 AA; 62171 MW; 28E99D9613941310 CRC64;
MRRFRPLNAP TPFLFFTGKG GVGKTSLACA TAIGLADRGL RVLLVSTDPA SNLDEMLGIA
LTDSPTSVPK VAGLSAMNID PEAAAESYRT RVLEQLGPGT TAGERSTVRE QLSGACTTEI
AAFDEFVGLL DGDEAGFNHI IFDTAPTGHT LRLLSLPKAW TGFLAGNDRG ASCLGPHSGL
KMQEDRFRQA LQALGDSRRT TIILVTRADR GAIREAARTS GELDALNLSN QILVVNGRFH
ATDPTDIVAV ALQRDQDEAL AAMPALLTKL PRDEIPLLGF DMVGLAALRA LLSSSNPPPP
PFATGDQDAE PVDLPGLDRL VDDIAQGTRG LIMVMGKGGV GKTTIAAAIA VGLAKRGHAV
HLSTTDPAAH VAFVVDGAMP GLTVDRIDPR IETKRYVAKI MASRGRDLDA QGRALLLEDL
ASPCTEEVAV FHAFSHVVAE ARSAFVVLDT APTGHTLLLL DATGAYHRQM TSQLEPSGAG
RIVTPLMRLQ DPTHTKVILV TLPETTPVSE AAALQEGLRR AGIEPFGWVI NKCLAASGTH
DPLLRLRLAR ELAQIARVQN GLAKRAFIIG WRNKPPIGIG ELQTLS
//
