ID A0A0Q7GQQ6_9FLAO Unreviewed; 739 AA.
AC A0A0Q7GQQ6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=MFS transporter {ECO:0000313|EMBL:KQX15911.1};
GN ORFNames=ASC72_03300 {ECO:0000313|EMBL:KQX15911.1};
OS Flavobacterium sp. Root420.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1736533 {ECO:0000313|EMBL:KQX15911.1, ECO:0000313|Proteomes:UP000051729};
RN [1] {ECO:0000313|EMBL:KQX15911.1, ECO:0000313|Proteomes:UP000051729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root420 {ECO:0000313|EMBL:KQX15911.1,
RC ECO:0000313|Proteomes:UP000051729};
RX PubMed=26633631; DOI=.1038/nature16192;
RA Bai Y., Muller D.B., Srinivas G., Garrido-Oter R., Potthoff E., Rott M.,
RA Dombrowski N., Munch P.C., Spaepen S., Remus-Emsermann M., Huttel B.,
RA McHardy A.C., Vorholt J.A., Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiota.";
RL Nature 528:364-369(2015).
RN [2] {ECO:0000313|Proteomes:UP000051729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root420 {ECO:0000313|Proteomes:UP000051729};
RA Garrido-Oter R., Bai Y.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000051729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root420 {ECO:0000313|Proteomes:UP000051729};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate)
CC is a mediator of the stringent response that coordinates a variety of
CC cellular activities in response to changes in nutritional abundance.
CC {ECO:0000256|RuleBase:RU003847}.
CC -!- SIMILARITY: Belongs to the relA/spoT family.
CC {ECO:0000256|RuleBase:RU003847}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQX15911.1}.
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DR EMBL; LMEF01000001; KQX15911.1; -; Genomic_DNA.
DR RefSeq; WP_056186643.1; NZ_LMEF01000001.1.
DR AlphaFoldDB; A0A0Q7GQQ6; -.
DR STRING; 1736533.ASC72_03300; -.
DR OrthoDB; 9805041at2; -.
DR Proteomes; UP000051729; Unassembled WGS sequence.
DR GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR CDD; cd00077; HDc; 1.
DR CDD; cd05399; NT_Rel-Spo_like; 1.
DR CDD; cd01668; TGS_RSH; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR004811; RelA/Spo_fam.
DR InterPro; IPR007685; RelA_SpoT.
DR InterPro; IPR004095; TGS.
DR InterPro; IPR012676; TGS-like.
DR InterPro; IPR033655; TGS_RelA/SpoT.
DR NCBIfam; TIGR00691; spoT_relA; 1.
DR PANTHER; PTHR21262:SF31; BIFUNCTIONAL (P)PPGPP SYNTHASE_HYDROLASE SPOT; 1.
DR PANTHER; PTHR21262; GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE; 1.
DR Pfam; PF13291; ACT_4; 1.
DR Pfam; PF13328; HD_4; 1.
DR Pfam; PF04607; RelA_SpoT; 1.
DR Pfam; PF02824; TGS; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00954; RelA_SpoT; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81271; TGS-like; 1.
DR PROSITE; PS51880; TGS; 1.
PE 3: Inferred from homology;
FT DOMAIN 402..463
FT /note="TGS"
FT /evidence="ECO:0000259|PROSITE:PS51880"
SQ SEQUENCE 739 AA; 84225 MW; 52242A64F8F2309D CRC64;
MIEIDIEKEN KAIAQEYKEL LRISYQTLTP ADKKLIRKAF DVAVDAHKEQ RRKSGEAYIF
HPIAVAKIVA SEIGLGATSI AAALLHDVVE DTPMTVEDIE RLFNPKVAQL VEGLTKISLV
QKDLNASMQA ENFRKMILTL NDDVRVILIK LADRLHNMQT MESMVEYKQT KIASETLYIY
APLAHRLGLY NIKTKLEDLG LKYTEPAVYN DIVSKIRETK EEQDAYIKDI SDVLKKSLDN
EDIDYIIKGR PKSIYSIRRK MRSQNVSFDE VYDKFALRIV YKADPHDEKF VAWKIYSIVT
DHYRPSPSRL RDWISSPKST GYEALHITVM GPKGRWVEVQ VRSERMDEIA EKGYAAHYKY
KNGASEESGL DVWLNLLREA LENPETNAVD FVEDFKMNLY SQEIFVFTPK GEIKSLPKGA
TSLDFAFSIH SEIGIKTRGT RVNGRLVPLN HELKSGDQVE VITSANQKPT VNWLEYVTTS
RAKNKIKNVL NENTKKIAEE GKELLTRKLK HLKITINEQV INELVNFFKL KTSLDLFYRV
GIGAIENQQL KDYAAQKSNT IINFFKNKIK RNKDTADEDI HKPVISSNYD MLVFGTEHDK
LDYKLSQCCN PIPGDDVFGF VTINEGIKVH KKDCPNAIGM QSNYAYRIMS AKWIDSSQEE
FKAIINITGM DVLGLTNQLT KVISNNMSVN IQSISLSTDA GIFHGQIAVI VKNNTILKKM
INAIKKVDGV DKVTREYRT
//
