ID A0A0Q7IY12_9BACL Unreviewed; 741 AA.
AC A0A0Q7IY12;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Membrane transport protein MMPL domain-containing protein {ECO:0000259|Pfam:PF03176};
GN ORFNames=ASD40_22035 {ECO:0000313|EMBL:KQX44678.1};
OS Paenibacillus sp. Root444D2.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1736538 {ECO:0000313|EMBL:KQX44678.1, ECO:0000313|Proteomes:UP000051657};
RN [1] {ECO:0000313|EMBL:KQX44678.1, ECO:0000313|Proteomes:UP000051657}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root444D2 {ECO:0000313|EMBL:KQX44678.1,
RC ECO:0000313|Proteomes:UP000051657};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQX44678.1, ECO:0000313|Proteomes:UP000051657}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root444D2 {ECO:0000313|EMBL:KQX44678.1,
RC ECO:0000313|Proteomes:UP000051657};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQX44678.1}.
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DR EMBL; LMEO01000053; KQX44678.1; -; Genomic_DNA.
DR RefSeq; WP_057307874.1; NZ_LMEO01000053.1.
DR AlphaFoldDB; A0A0Q7IY12; -.
DR STRING; 1736538.ASD40_22035; -.
DR Proteomes; UP000051657; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000051657};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 192..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 565..582
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 589..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 625..644
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 665..688
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 56..385
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 415..727
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
SQ SEQUENCE 741 AA; 82107 MW; 1F58E0EE17F936C8 CRC64;
MNRFLPQLAR FVSSSKGVKI VLISWLAAII LLSAIAPSSK EVAKSGGEGS IHENTLSAAA
QQILKEDYPS QDGLTALLVF HGQNAITDVE RRNIEKISEW LSSDQKPPLI TRAVPFHQLP
KPQQDSLFSE DQTTLLLTVS LQKDLESGQV YETLEQIRHT ADQIGLGAVG LEITGPAGIS
SDTIMLFKKA DFVLMLATVV LILVILIIIY RSPLLALLPL VIAGMVYQVV DRILGLAGKM
GWFFVEKQSL SIMMILLFAV LTDYCLFIVA RYRSELRKTD SKYDAMSTAF SKVAEPILFS
GGTVFIAMLT LFAAIFKPYH HFAPVFSVAM IIILLGGLTL IPAVFALVGR KAFWPLIPKR
EMTLSEVKQK GFWAKISVFI TKKPAFTAVL LLIVLIIPSF TTLSMNYSFN LMKSFPNDIS
SRQGFELLQQ RFPQGQLAPV TVLLKSEKEI VLDAAFIDKT RLLVNAMKER NGISGITPEI
NQNLLTPGNP TALTILSKQK HTIKLQMTLK QNPYDQEALD LINQMRANSE QLLRDSGFDP
AQFSLHYAGQ TADQLDVRSM NRRDTLVLFS LITVFITLML IWQARSIRLA FTMIATMLLS
YAATMGLVWS VFHYGFGYDA FSYRLPVYTF VFLIALGVDY NIVLVSRIKE EAQNYVWKEA
VGRGVALTGG VISSAGIVLA ATFSVLMTQP LQELMLFGFA MAAGILIDTF LVRGMLLPAL
MTYLAPKGAD TRLQQSKAVN L
//
