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Database: UniProt
Entry: A0A0Q7LLD4_9BURK
LinkDB: A0A0Q7LLD4_9BURK
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ID   A0A0Q7LLD4_9BURK        Unreviewed;       372 AA.
AC   A0A0Q7LLD4;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   08-MAY-2019, entry version 19.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=ASD34_03630 {ECO:0000313|EMBL:KQX90364.1};
OS   Variovorax sp. Root473.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Variovorax.
OX   NCBI_TaxID=1736541 {ECO:0000313|EMBL:KQX90364.1, ECO:0000313|Proteomes:UP000051275};
RN   [1] {ECO:0000313|EMBL:KQX90364.1, ECO:0000313|Proteomes:UP000051275}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Root473 {ECO:0000313|EMBL:KQX90364.1,
RC   ECO:0000313|Proteomes:UP000051275};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KQX90364.1, ECO:0000313|Proteomes:UP000051275}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Root473 {ECO:0000313|EMBL:KQX90364.1,
RC   ECO:0000313|Proteomes:UP000051275};
RA   Schulze-Lefert P.;
RT   "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KQX90364.1}.
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DR   EMBL; LMEV01000014; KQX90364.1; -; Genomic_DNA.
DR   RefSeq; WP_056575631.1; NZ_LMEV01000014.1.
DR   EnsemblBacteria; KQX90364; KQX90364; ASD34_03630.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000051275; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000051275};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:KQX90364.1}.
FT   DOMAIN       62    360       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   372 AA;  40495 MW;  78C678A0D0038EFF CRC64;
     MSTNTPPAGD SWYASVEKTS KTDDERIKDI NVLPPPEHLI RFFPIRGTPI EALISGTRRG
     IHNIMAGKDD RLLVVMGPCS IHDPAAALEY ARRLKAERDK YAGTLEIVMR VYFEKPRTTV
     GWKGLINDPY LDESYRIDEG LRIARQLLID INRLGLPAGS EFLDVISPQY IGDLIAWGAI
     GARTTESQVH RELASGLSAP IGFKNGTDGN IRIATDAIQA AARGHHFLSV HKNGQVAIVQ
     TNGNRDCHVI LRGGKTPNYD AASVEAACKD LEAAKLPPTL MVDCSHANSS KQHQKQIDVA
     KDIAGQIAGG SNRVFGVMIE SHLQAGAQKF TPGKDQLSGL EYGKSITDAC IGWDDSVQVL
     ETLSQAVKQR RG
//
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