ID A0A0Q7UFL8_9MICO Unreviewed; 547 AA.
AC A0A0Q7UFL8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=ASD19_13060 {ECO:0000313|EMBL:KQZ06026.1};
OS Microbacterium sp. Root53.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=1736553 {ECO:0000313|EMBL:KQZ06026.1, ECO:0000313|Proteomes:UP000051407};
RN [1] {ECO:0000313|Proteomes:UP000051407}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root53 {ECO:0000313|Proteomes:UP000051407};
RA Garrido-Oter R., Bai Y.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQZ06026.1, ECO:0000313|Proteomes:UP000051407}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root53 {ECO:0000313|EMBL:KQZ06026.1,
RC ECO:0000313|Proteomes:UP000051407};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC {ECO:0000256|ARBA:ARBA00006637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQZ06026.1}.
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DR EMBL; LMFR01000010; KQZ06026.1; -; Genomic_DNA.
DR RefSeq; WP_055988989.1; NZ_LMFR01000010.1.
DR AlphaFoldDB; A0A0Q7UFL8; -.
DR STRING; 1736553.ASD19_13060; -.
DR OrthoDB; 3713880at2; -.
DR Proteomes; UP000051407; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18029; DEXHc_XPB; 1.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:KQZ06026.1};
KW Helicase {ECO:0000313|EMBL:KQZ06026.1};
KW Hydrolase {ECO:0000313|EMBL:KQZ06026.1};
KW Nucleotide-binding {ECO:0000313|EMBL:KQZ06026.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051407}.
FT DOMAIN 190..344
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 398..545
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 547 AA; 60809 MW; A3B02A46A754B976 CRC64;
MADGPLIVQS DRTVLLEVAH PDAETARHEL AIFAELERAP EHIHTYRITR LGLWNARAAG
HTADDMLQTL DRWSRFPVPP SVSVDIRETV ERYGRLSIRR GDEGELLLTS TDRAVLAEVS
RNKRIQPLLI AQPSPETYVV DAWARGHIKQ ELLKIGWPAE DLAGYTPGTP HPIDLDEDGW
ALRPYQAEAV EKFSEGGSGV VVLPCGAGKT LVGAGAMAVT RTTTLILVTN TVSARQWRDE
LLKRTSLTPE EIGEYSGQTK EIKPVTIATY QILTARRRGE YPHLALLDAL DWGLIVYDEV
HLLPAPVFKL TADLQARRRL GLTATLVRED GREGDVFSLI GPKRFDAPWK EIEAQGFISP
AACYEVRVDL PPSERLEYAA SADEDRYRLA ATAPAKIDVV KSLIAKHPDE QILVIGQYLE
QLDELSEALD APKITGSTPV DERERLFQAF REGTINLLVV SKVANFSVDL PEASVAIQVS
GSFGSRQEEA QRLGRLLRPK QSNHTASFYT LIARDTVDQD FAQNRQRFLA EQGYSYTILD
AERLEAA
//
