ID A0A0Q8DAV9_9ACTN Unreviewed; 647 AA.
AC A0A0Q8DAV9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Acetoacetyl-CoA synthetase {ECO:0000313|EMBL:KRA28234.1};
DE EC=6.2.1.16 {ECO:0000313|EMBL:KRA28234.1};
GN ORFNames=ASD81_23075 {ECO:0000313|EMBL:KRA28234.1};
OS Nocardioides sp. Root614.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=1736571 {ECO:0000313|EMBL:KRA28234.1, ECO:0000313|Proteomes:UP000051699};
RN [1] {ECO:0000313|EMBL:KRA28234.1, ECO:0000313|Proteomes:UP000051699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root614 {ECO:0000313|EMBL:KRA28234.1,
RC ECO:0000313|Proteomes:UP000051699};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KRA28234.1, ECO:0000313|Proteomes:UP000051699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root614 {ECO:0000313|EMBL:KRA28234.1,
RC ECO:0000313|Proteomes:UP000051699};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRA28234.1}.
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DR EMBL; LMGV01000010; KRA28234.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0Q8DAV9; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000051699; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:KRA28234.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000051699}.
FT DOMAIN 32..85
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 94..463
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 647 AA; 70487 MW; 8EA17DBDDAAE68F2 CRC64;
MRPAFTGAEL AATGLGKYVA WLADHGRRFD TYHDLWAWSV DDLEDFWASL WDFYDVAGSR
GNCVLADRAM PGASWFPTAR LNYAESVLGG VDDPSRVAIV GRSQTRAPVE LTFGELTDQV
RRARAAFQSL GVRKGDRVVG YLPNVPEAVV AMLATASLGA TWACCPPEFG AKSVIDRLAQ
LEPTLLIAVS GYTYGTKEVD RTAELQTIRA ALPTVRDVVG LTYGIHTVPD AHVWEWLLEE
QSTEVPLEFE PVSFDHPLWT LFSSGTTGLP KAVVHSHGGI TLEHLKLHGL HLDTRDGDRV
LLMTTTGWTV WNCLVSALMV GASIVVTDGN PLHPDLEEPW RTVAETGVTL FGTSPGYLMA
CRNESMRPGD TFDLSAVRTL GVTGAVLPAE AYDWLYDVLP ADVYLNSMSG GTDICSNFVS
GNPWVPVYRG ELSAPTLGAD VAAFDDDGNE VTDQVGELVI RAPMPSMPVA FWNDNDMERY
LAAYFDIYPG IWRHGDWVTV SDRQSVVIQG RSDATLNRGG VRIGTAEFYN LIEALPEVED
SLVVHLEDLT GGPGELMLFV QLAEGHEMDA DTVKALKTII RRELSPRHVP DLVAAVPAVP
RTLTGKKLET PIKKILAGAP PERVVSPGSV TNYDAIEAYR IAALKTV
//
