ID   A0A0Q8E163_9ACTN        Unreviewed;       345 AA.
AC   A0A0Q8E163;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Adenosine deaminase {ECO:0000313|EMBL:KRA38108.1};
GN   ORFNames=ASD81_05455 {ECO:0000313|EMBL:KRA38108.1};
OS   Nocardioides sp. Root614.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=1736571 {ECO:0000313|EMBL:KRA38108.1, ECO:0000313|Proteomes:UP000051699};
RN   [1] {ECO:0000313|EMBL:KRA38108.1, ECO:0000313|Proteomes:UP000051699}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Root614 {ECO:0000313|EMBL:KRA38108.1,
RC   ECO:0000313|Proteomes:UP000051699};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KRA38108.1, ECO:0000313|Proteomes:UP000051699}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Root614 {ECO:0000313|EMBL:KRA38108.1,
RC   ECO:0000313|Proteomes:UP000051699};
RA   Schulze-Lefert P.;
RT   "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRA38108.1}.
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DR   EMBL; LMGV01000001; KRA38108.1; -; Genomic_DNA.
DR   RefSeq; WP_056707596.1; NZ_LMGV01000001.1.
DR   AlphaFoldDB; A0A0Q8E163; -.
DR   OrthoDB; 105475at2; -.
DR   Proteomes; UP000051699; Unassembled WGS sequence.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   NCBIfam; TIGR01430; aden_deam; 1.
DR   PANTHER; PTHR43114; ADENINE DEAMINASE; 1.
DR   PANTHER; PTHR43114:SF6; ADENINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000051699}.
FT   DOMAIN          14..340
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   345 AA;  36684 MW;  CFF4A0DF4F0BC3AF CRC64;
     MPPSPLPGFI AGLPKAELHV HHVGSASERI VSELAERHPG TVPSDPVLLR EFFAFRDFAH
     FIQVYLAVVD LVKTPEDVRY LTYEIGRELA EGQSVRYAEL TCTPYTSVLP DTPGLGMPIE
     AYTEAIEDAG VAAERDFGLV LRWIYDIPGE SGLPAADATL RFALDHRPDG LIGFGLGGPE
     IGVAREQFIP HFAAARAAGL HSIPHAGETT GPETIWTSIR DLGAERIGHG TSAAADPALL
     AHLAEHQIPL EVCPSSNIAT RAVATLADHP LPIFVEAGVL VTINSDDPPM FGTTLNREYE
     IAADLLGLDA ADLADLSRAA VGASFAPADV KARLLGEIDA YVAAE
//