ID A0A0Q8LWI9_9MICO Unreviewed; 774 AA.
AC A0A0Q8LWI9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Competence protein ComEC {ECO:0000313|EMBL:KRB38152.1};
GN ORFNames=ASD93_05140 {ECO:0000313|EMBL:KRB38152.1};
OS Microbacterium sp. Root180.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=1736483 {ECO:0000313|EMBL:KRB38152.1, ECO:0000313|Proteomes:UP000050802};
RN [1] {ECO:0000313|EMBL:KRB38152.1, ECO:0000313|Proteomes:UP000050802}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root180 {ECO:0000313|EMBL:KRB38152.1,
RC ECO:0000313|Proteomes:UP000050802};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KRB38152.1, ECO:0000313|Proteomes:UP000050802}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root180 {ECO:0000313|EMBL:KRB38152.1,
RC ECO:0000313|Proteomes:UP000050802};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRB38152.1}.
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DR EMBL; LMHS01000002; KRB38152.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0Q8LWI9; -.
DR STRING; 1736483.ASD93_05140; -.
DR Proteomes; UP000050802; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000050802};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 531..721
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 774 AA; 77100 MW; A8539E1130F6A982 CRC64;
MAGAAWVTAW CATRWPDAAA GVALALWAAC LGALALFAMW ATAGRTRTAR VSALVMVIAI
AAGAAAASHV ALANPSRHAV LGLEIMNGRA VIVEATVVGK VERRADGALA FDAHVSRIAT
GAESALVSAE AVVRVAPGDV ESSADLDLGA VVEARGTASA ARPGERAVIT VRASRGVAVT
RPPIGIAHTT ATLRQELVRS VRGLPGDGAS LVPGLAVGDT SAVPAELDAA MKEASLSHLT
AVSGANCALV VGLAFAAAAA LGASRAVRVS AGLAALVGFI VLVTPEPSVV RAGAMAAVAM
LGVLLGRPGA GTAILSLCVA ALLVADPWLA GSLGFALSVA ATASLLLFAR PLAQGLARRL
PRALALGLSV PLAAQLACGP LLVLIAPQVP VYGVVANLLA APAAPIATIV GLAACLAAPI
PPLQDGLAAI AWLPASWIAG TAVATSALPG DLVPWLEGWP GAFALGGVGL AIGLLIALRR
GTPLRALVRG ASVVIVALVI GAATGGGLLA TLAGRWTLPA EWSILACDVG QGDAVLLRSA
GAVALIDTGP EPEPLAACLD RTGVGQIDLL VLSHFDLDHV GGVAAVEGRV GTVLHGPADE
DGAAILDRLQ SAGAELVDAR AGLTGTLGDA RWRAVWPPPE GRAFPMGNDA SVVLDVRGGG
IPPIVLLGDL SASPQRAIAA GGGLDPPYAV VKVAHHGSAD QDAGLYRQAA PALALVTVGA
ENDYGHPRAE ILDELNALDA RIARTDAEGV VAVWEGADGL EVWREREVGV GGDG
//
