ID   A0A0Q8P2A3_9BURK        Unreviewed;       513 AA.
AC   A0A0Q8P2A3;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:KRB66257.1};
DE            EC=1.1.1.157 {ECO:0000313|EMBL:KRB66257.1};
GN   ORFNames=ASE07_10250 {ECO:0000313|EMBL:KRB66257.1};
OS   Noviherbaspirillum sp. Root189.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Oxalobacteraceae; Noviherbaspirillum.
OX   NCBI_TaxID=1736487 {ECO:0000313|EMBL:KRB66257.1, ECO:0000313|Proteomes:UP000051303};
RN   [1] {ECO:0000313|EMBL:KRB66257.1, ECO:0000313|Proteomes:UP000051303}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Root189 {ECO:0000313|EMBL:KRB66257.1,
RC   ECO:0000313|Proteomes:UP000051303};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KRB66257.1, ECO:0000313|Proteomes:UP000051303}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Root189 {ECO:0000313|EMBL:KRB66257.1,
RC   ECO:0000313|Proteomes:UP000051303};
RA   Schulze-Lefert P.;
RT   "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Lipid metabolism; butanoate metabolism.
CC       {ECO:0000256|ARBA:ARBA00005086}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRB66257.1}.
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DR   EMBL; LMHZ01000078; KRB66257.1; -; Genomic_DNA.
DR   RefSeq; WP_057293800.1; NZ_LMHZ01000078.1.
DR   AlphaFoldDB; A0A0Q8P2A3; -.
DR   STRING; 1736487.ASE07_10250; -.
DR   OrthoDB; 5287258at2; -.
DR   Proteomes; UP000051303; Unassembled WGS sequence.
DR   GO; GO:0008691; F:3-hydroxybutyryl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   PANTHER; PTHR48075:SF5; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   Pfam; PF00725; 3HCDH; 2.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000313|EMBL:KRB66257.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051303}.
FT   DOMAIN          16..194
FT                   /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF02737"
FT   DOMAIN          196..293
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
FT   DOMAIN          422..503
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
SQ   SEQUENCE   513 AA;  54485 MW;  085BE74367FDC00B CRC64;
     MQNGMRPEPT SPQLVVGLVG CGIMGRGIAQ IAVLSGAQVR LTDAREGAAK VAREELLATF
     GKLVDKGKLD AAAASAAGER LQACTGIEQL AGCHVVVEAI VEDLAAKRSL FTTLEGIVTA
     DTILATNTSS LPVTAIAAGL KHPERVAGFH FFNPVPLMKI VEAIGGFLTE ASVVDYLLAL
     GKHWGHTAVR AKDTPGFIVN HAGRGYGTEG LRLLAEGVAT VPVLDNILRD TAGFRLGPCE
     LLDLTGLDVS HPVMESIYHQ YYEEPRFRPQ VHTRQMLTAG ALGKKVGHGF YRYGSDGKKE
     ALAEPAQATA TASSVWLSQE RPELAEKIAP FIAAAGIPLE SGAHPSDTAL CIVTPLGEDA
     TTCCVRENLD ARRTVAVESL LDLSRRRVVM TTPATSADYL AMACGLFGAT GTPVSVIRDS
     AGLVTQRVVA HIVNIACEIA QQDIADPQDI DRAVTLGLGY PLGPLAWGDQ IGARTVLAIL
     KNLEQQTGDS RYRPSPWLQR RALLGLSLHH KEI
//