ID   A0A0Q8Q2I0_9SPHN        Unreviewed;       485 AA.
AC   A0A0Q8Q2I0;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:KRB79756.1};
GN   ORFNames=ASE00_18780 {ECO:0000313|EMBL:KRB79756.1};
OS   Sphingomonas sp. Root710.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=1736594 {ECO:0000313|EMBL:KRB79756.1, ECO:0000313|Proteomes:UP000051854};
RN   [1] {ECO:0000313|EMBL:KRB79756.1, ECO:0000313|Proteomes:UP000051854}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Root710 {ECO:0000313|EMBL:KRB79756.1,
RC   ECO:0000313|Proteomes:UP000051854};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KRB79756.1, ECO:0000313|Proteomes:UP000051854}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Root710 {ECO:0000313|EMBL:KRB79756.1,
RC   ECO:0000313|Proteomes:UP000051854};
RA   Schulze-Lefert P.;
RT   "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Lipid metabolism; butanoate metabolism.
CC       {ECO:0000256|ARBA:ARBA00005086}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRB79756.1}.
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DR   EMBL; LMIB01000017; KRB79756.1; -; Genomic_DNA.
DR   RefSeq; WP_056383491.1; NZ_LMIB01000017.1.
DR   AlphaFoldDB; A0A0Q8Q2I0; -.
DR   STRING; 1736594.ASE00_18780; -.
DR   OrthoDB; 9771883at2; -.
DR   Proteomes; UP000051854; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR   Gene3D; 1.10.1040.50; -; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR041040; 3HCDH_RFF.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   PANTHER; PTHR48075:SF5; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   Pfam; PF00725; 3HCDH; 2.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   Pfam; PF18321; 3HCDH_RFF; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000051854}.
FT   DOMAIN          9..186
FT                   /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF02737"
FT   DOMAIN          189..285
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
FT   DOMAIN          360..405
FT                   /note="3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-
FT                   fold"
FT                   /evidence="ECO:0000259|Pfam:PF18321"
FT   DOMAIN          407..480
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
SQ   SEQUENCE   485 AA;  49662 MW;  8050FC01429605B9 CRC64;
     MEIRSNAPIA VIGAGTMGAG IAQVAATAGH PVTVIDQAED ALERGRATVA AALDQALRKG
     RLDESARDAI AARITWATDI AATAGHALAI EAIVERLDIK QALVTALAGA MPPDALIASN
     TSSLGIGDIA AILDRPERFL GLHFFNPVPA MKLVEVIAGP ATDPAAVNAA ADLMRAWGKR
     PVIVRDVPGF IVNRVARPYY GEGFAALGEG IDPALIDAAL TGGGGFRMGP LALADLIGHD
     VNFAVASSVY DSYDGKTRFR PQDAQRALRD GGQLGRKSGT GVYDYAQDLP APPYAAPAAA
     PASIAIYQLD QLAPLGAEAR AAGIAVTDGP AIGADMARIG NSMMALGDGR PLGERPGVDV
     LIDQCRDFAS ASVSVISATS PAHAEAAAGL LQAIGRKVLV IPDRPGQIVL RTLAQLANAA
     ADAVTDDVAD ADGIDDAMIH GANHPEGPLG WARRVGQGRV RAALDNIATA SGDAMYQPSS
     YFGAP
//