ID A0A0Q8QLE6_9SPHN Unreviewed; 469 AA.
AC A0A0Q8QLE6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=His-Xaa-Ser system radical SAM maturase HxsB {ECO:0000313|EMBL:KRB86533.1};
GN ORFNames=ASE00_07495 {ECO:0000313|EMBL:KRB86533.1};
OS Sphingomonas sp. Root710.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1736594 {ECO:0000313|EMBL:KRB86533.1, ECO:0000313|Proteomes:UP000051854};
RN [1] {ECO:0000313|EMBL:KRB86533.1, ECO:0000313|Proteomes:UP000051854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root710 {ECO:0000313|EMBL:KRB86533.1,
RC ECO:0000313|Proteomes:UP000051854};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KRB86533.1, ECO:0000313|Proteomes:UP000051854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root710 {ECO:0000313|EMBL:KRB86533.1,
RC ECO:0000313|Proteomes:UP000051854};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the radical SAM superfamily. Anaerobic
CC sulfatase-maturating enzyme family. {ECO:0000256|ARBA:ARBA00023601}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRB86533.1}.
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DR EMBL; LMIB01000001; KRB86533.1; -; Genomic_DNA.
DR RefSeq; WP_056378662.1; NZ_LMIB01000001.1.
DR AlphaFoldDB; A0A0Q8QLE6; -.
DR STRING; 1736594.ASE00_07495; -.
DR OrthoDB; 9810775at2; -.
DR Proteomes; UP000051854; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR024023; rSAM_paired_HxsB.
DR InterPro; IPR023867; Sulphatase_maturase_rSAM.
DR NCBIfam; TIGR03978; rSAM_paired_1; 1.
DR PANTHER; PTHR43273; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR PANTHER; PTHR43273:SF3; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01072; dehydrogenase_like; 1.
DR SFLD; SFLDG01384; thioether_bond_formation_requi; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000051854};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 87..202
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|Pfam:PF04055"
SQ SEQUENCE 469 AA; 52928 MW; 541E6D09CDAB9D50 CRC64;
MTAVSLRARA GADGRALYID TAGRFFRSDE ALLDRWRQDA LVETERAALV ERGVVIELEG
GLSHLAALYG EARRSSSVER LDYLILVPTL RCNLSCSYCQ VSRADERAQG YDWSDATLEA
VLTLLRGLDT PSIKIEFQGG EPTLRLDLIE AVIAACDRFE RADFVICTNL ATLDEATLQL
LGRKNLHVST SLDGPMNIHQ RQRTLTSIAT DTFAANLATI IECYGPDKVS ALPTIDPRDP
PAIDSLIDAF VERGLHQIFL RPINYQGFAR KRHSHARDVE QAWLSYQTQF MRALIVRNWA
DRSRVLEESY FSIILRRIFQ PGHDRHVDLR NPNTVGTDYI VVDYDGAVYP TDEARMLTRS
GVIDLRIGDV INGWDSEARK VINAHCDNRD DPTCAACAYQ PYCGRDVIDD LARYGTIDLP
REETAFCQRH LSLFDLAFDL IYDPDPAVQY SLRRWLKVRG DNIVLGDEL
//
