ID A0A0Q8YXX0_9ACTN Unreviewed; 720 AA.
AC A0A0Q8YXX0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=ASE41_37535 {ECO:0000313|EMBL:KRC99132.1};
OS Streptomyces sp. Root264.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1736503 {ECO:0000313|EMBL:KRC99132.1, ECO:0000313|Proteomes:UP000051177};
RN [1] {ECO:0000313|EMBL:KRC99132.1, ECO:0000313|Proteomes:UP000051177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root264 {ECO:0000313|EMBL:KRC99132.1,
RC ECO:0000313|Proteomes:UP000051177};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KRC99132.1, ECO:0000313|Proteomes:UP000051177}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root264 {ECO:0000313|EMBL:KRC99132.1,
RC ECO:0000313|Proteomes:UP000051177};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRC99132.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LMIZ01000059; KRC99132.1; -; Genomic_DNA.
DR RefSeq; WP_057583784.1; NZ_LMIZ01000059.1.
DR AlphaFoldDB; A0A0Q8YXX0; -.
DR STRING; 1736503.ASE41_37535; -.
DR OrthoDB; 2365435at2; -.
DR Proteomes; UP000051177; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000051177};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 179..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 525..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 550..572
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 584..603
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 624..645
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 651..671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 205..337
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 698..720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 720 AA; 75932 MW; 7E11B84896868FF5 CRC64;
MTGNRGIAHL VCGRRAKWLV LALWVVVLFL TAPFAQKLAD AQDNDAASWL PGSAESTQVL
EISKDFRPEQ IPAVVVYARD GGLTVQDRAA IDRDAAEIRG LHDHGIRGAE TRGPVYDRAT
DPRAAQIFVP ITMDESGWQR IAPAVDSIRD VVGDGGAGLA VHITGPGGTS ADFSKAFEGI
DSTLLVSAMA VVVVMLLITY RSPSLLLVPV IGVVAALFTA QALIYFLAQH AGLTVNGQSA
GILTVLVFGA GTDYALLLVA RYREELRRHE DRHEAMALAL HRAGPAVLAS GATVVLSMLV
LLAAEMNSTR GLGPVAAIGV AVALIAMMTL FPALLVICGR WIFWPVIPHF GSDEPTEHGV
WARTGRSFAR RPRMIWAVTA LVLAVCSLGL IQLRAEGISN ADAFTGTPDS ITGQKVSGRY
FPAGSGDPLM IVSDQDRAKE VRRTVAATEG VVPTSLGVPP GAKPVHEGRV LLEATMTAPA
DSEAAKQTVE RVRDAVHEVP DADALVGGGT AALLDMDKAT THDNLLIIPL VLVVVLLILC
GLLRALIAPL VLVGTVILSF AAALGISALA FRHVFDYAGE ATDFPLFVFV FLVALGIDYN
IFLTTRIREE AARQGTRAGV VTGLAATGAV ITSAGLVLAG TFAALGTLPM VAFAEIGFAV
ALGVLLDTFI VRSVLVTSLF LDIGPKVWWP HRLSRETAGR PEAAPGDGHP GTVRKDEPFA
//
