ID A0A0Q9EB38_9GAMM Unreviewed; 329 AA.
AC A0A0Q9EB38;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=3-beta hydroxysteroid dehydrogenase {ECO:0000313|EMBL:KRD65686.1};
GN ORFNames=ASE45_16900 {ECO:0000313|EMBL:KRD65686.1};
OS Lysobacter sp. Root96.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Lysobacter.
OX NCBI_TaxID=1736612 {ECO:0000313|EMBL:KRD65686.1, ECO:0000313|Proteomes:UP000050805};
RN [1] {ECO:0000313|EMBL:KRD65686.1, ECO:0000313|Proteomes:UP000050805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root96 {ECO:0000313|EMBL:KRD65686.1,
RC ECO:0000313|Proteomes:UP000050805};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KRD65686.1, ECO:0000313|Proteomes:UP000050805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Root96 {ECO:0000313|EMBL:KRD65686.1,
RC ECO:0000313|Proteomes:UP000050805};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|ARBA:ARBA00009219}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRD65686.1}.
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DR EMBL; LMJN01000005; KRD65686.1; -; Genomic_DNA.
DR RefSeq; WP_055905112.1; NZ_LMJN01000005.1.
DR AlphaFoldDB; A0A0Q9EB38; -.
DR STRING; 1736612.ASE45_16900; -.
DR OrthoDB; 3174087at2; -.
DR Proteomes; UP000050805; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000050805}.
FT DOMAIN 4..252
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 329 AA; 34801 MW; 8ABBDDA49EA52EC8 CRC64;
MKVLVTGGGG FLGQALCRGL VERGYEVVSY NRGLYPALDA LGVIQAQGDL ADREAVIAAA
RGCEAVFHNA AKAGAWGSYD SYHQANVVGT DNVLAACRAH GIGRLVYTST PSVTHRATHP
VEGGTADTVP YGEGFKAPYA TTKAIAEKAV LAANAPSLAT VALRPRLIWG VGDNQLLPRL
VARAEAGRLR FVGDGYNKVD TTYIDNAAQA HFDAFDHLAP AAACAGRAYF ISNGEPKTMR
ETLNSLLAAV GAPQVDKTLP FGAAYAIGAV CEGLWHALPL KGEPPMTRFL AEQLATSHWY
DMAPATRDFG YVPRVSFHEG LTRLKAACT
//
