ID A0A0Q9LSG1_9MICO Unreviewed; 818 AA.
AC A0A0Q9LSG1;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=PASTA domain-containing protein {ECO:0000259|PROSITE:PS51178};
GN ORFNames=ASG70_04145 {ECO:0000313|EMBL:KRE56332.1};
OS Phycicoccus sp. Soil748.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Phycicoccus.
OX NCBI_TaxID=1736397 {ECO:0000313|EMBL:KRE56332.1, ECO:0000313|Proteomes:UP000051855};
RN [1] {ECO:0000313|Proteomes:UP000051855}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Soil748 {ECO:0000313|Proteomes:UP000051855};
RA Garrido-Oter R., Bai Y.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KRE56332.1, ECO:0000313|Proteomes:UP000051855}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Soil748 {ECO:0000313|EMBL:KRE56332.1,
RC ECO:0000313|Proteomes:UP000051855};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-
CC Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-
CC (1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-
CC cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-
CC D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl
CC diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+);
CC Xref=Rhea:RHEA:23708, Rhea:RHEA-COMP:9602, Rhea:RHEA-COMP:9603,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:58405, ChEBI:CHEBI:60033,
CC ChEBI:CHEBI:78435; EC=2.4.1.129;
CC Evidence={ECO:0000256|ARBA:ARBA00023988};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRE56332.1}.
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DR EMBL; LMSC01000006; KRE56332.1; -; Genomic_DNA.
DR RefSeq; WP_056883046.1; NZ_LMSC01000006.1.
DR AlphaFoldDB; A0A0Q9LSG1; -.
DR STRING; 1736397.ASG70_04145; -.
DR OrthoDB; 9766909at2; -.
DR Proteomes; UP000051855; Unassembled WGS sequence.
DR GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd06577; PASTA_pknB; 1.
DR Gene3D; 3.30.10.20; -; 1.
DR Gene3D; 1.10.3810.10; Biosynthetic peptidoglycan transglycosylase-like; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR001264; Glyco_trans_51.
DR InterPro; IPR023346; Lysozyme-like_dom_sf.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR036950; PBP_transglycosylase.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR32282; BINDING PROTEIN TRANSPEPTIDASE, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR32282:SF33; PEPTIDOGLYCAN GLYCOSYLTRANSFERASE; 1.
DR Pfam; PF03793; PASTA; 1.
DR Pfam; PF00912; Transgly; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SMART; SM00740; PASTA; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF53955; Lysozyme-like; 1.
DR PROSITE; PS51178; PASTA; 1.
PE 4: Predicted;
KW Carboxypeptidase {ECO:0000256|ARBA:ARBA00022645};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Protease {ECO:0000256|ARBA:ARBA00022670}.
FT DOMAIN 716..780
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT REGION 776..818
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 781..801
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 818 AA; 86728 MW; F942ED552A62A5C7 CRC64;
MSGRATNLGN VVSLLGAFVA SAMVMGLLAA GLLIPAVGAA GSAATSGVKM FDDLPGEFTA
SALSQQSRIV DAKGNVLATP QQENRIIVNL KDVAPIMRKA QVAIEDSRFY EHGGVDPRGI
LRAAVSNAQG GDTQGASTLT QQFVKLTLQE NALRNNDEEA AKAAVRVSAA RKIQEIKYAV
TLEKEMTKDQ ILQGYMNLAY YGDLAYGVEA ASQHYFSIPS AKLNLSQAAL LAGLVQNPSR
TDPIHFPERA QARRNVVLDR MHDLGIVTDK QWKTAKAVPV KKMLKVKNPV SNCMASSEPY
FCNYVMEYLK DTSNHGLDAL GKSTPERIKN LTGGGLTIQT TLDATVQAQA RQDVLKKVPF
ANHALPRDAA DKTKLGLSQM VGSAASIVEP STGRVLAMVQ NSKYPTTKKE QSSYGYTQVN
WNVDTKYQGT TGFQFGSTAK MFAIVRALET GTPVSGTVPS KFASPTKPAY YSYQEQGPCG
DPKGWSVHND YAVGGKPIPL KKATADSINT AFASLSMKLG TTKVRDTMTK MHLLQGDGSK
IGCNPSAVLG TGVVTPLTLA SSYATLANNG KYCPPNPILS ITTADKKPLK IGTPTCKQVI
DPDVAKGATE LLTGVIKNGT GVRAKLGARP AAGKTGTTDD HVESWFVGYT AQRATAVWVG
TPYSQQGMRH ITLAGQSYSG VFGGDIAAPI WKDLTEAASQ GLPIRDFDTP SDKILNGDRV
AVPFVGGMTV EEATARLKEA GFNAQVAGST NSGYSRGIVV YTDPSGTAMR GSTVSLYTST
GYVPPPPPKS TPKPTSTPKP TATTPKPTKT KKPPPPKK
//
