ID A0A0Q9QH90_9ACTN Unreviewed; 549 AA.
AC A0A0Q9QH90;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=ASG76_18040 {ECO:0000313|EMBL:KRE96932.1};
OS Nocardioides sp. Soil774.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=1736408 {ECO:0000313|EMBL:KRE96932.1, ECO:0000313|Proteomes:UP000051100};
RN [1] {ECO:0000313|EMBL:KRE96932.1, ECO:0000313|Proteomes:UP000051100}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Soil774 {ECO:0000313|EMBL:KRE96932.1,
RC ECO:0000313|Proteomes:UP000051100};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KRE96932.1, ECO:0000313|Proteomes:UP000051100}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Soil774 {ECO:0000313|EMBL:KRE96932.1,
RC ECO:0000313|Proteomes:UP000051100};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC {ECO:0000256|ARBA:ARBA00006637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRE96932.1}.
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DR EMBL; LMSM01000002; KRE96932.1; -; Genomic_DNA.
DR RefSeq; WP_056599561.1; NZ_LMSM01000002.1.
DR AlphaFoldDB; A0A0Q9QH90; -.
DR STRING; 1736408.ASG76_18040; -.
DR OrthoDB; 3713880at2; -.
DR Proteomes; UP000051100; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18029; DEXHc_XPB; 1.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
DR Pfam; PF04851; ResIII; 1.
DR PRINTS; PR00851; XRODRMPGMNTB.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:KRE96932.1};
KW Helicase {ECO:0000313|EMBL:KRE96932.1};
KW Hydrolase {ECO:0000313|EMBL:KRE96932.1};
KW Nucleotide-binding {ECO:0000313|EMBL:KRE96932.1}.
FT DOMAIN 190..344
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 398..545
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 549 AA; 60469 MW; 0D1A0B2D7F64CFC6 CRC64;
MNDGPLIVQS DKTLLLEVDH PSAPDARKAI APFAELERSP EHIHTYRLTP LGLWNARAAG
HDAEQVVDAL LTWSRYAVPH ALLVDVAETM GRYGRLRLEK HPVHGLVLSS TDRPVLEEVL
RAKKIAGMVG ARLDDDSVAV HPSERGNLKQ ALLKLGWPAE DFAGYVDGEA HAIDLAEDEW
TLRPYQREAA QSFWDGGSGV VVLPCGAGKT LVGAASMAHA QATTLILVTN TVSARQWKDE
LVARTSLTAD EIGEYSGAVK EIRPVTIATY QVLTTKRKGV YPHLELLDAR DWGLIVYDEV
HLLPAPIFRM TADLQARRRL GLTATLVRED GREGEVFSLI GPKRYDAPWK DIEAQGYIAP
ADCVEVRVTL PDGERLAYAT SDPDTRYRLA SCTHAKIDVV RDLVRQHAGQ PTLVIGQYID
QLDEIAAMLD APVIKGETPV KERQRLFNAF RAGEIGLLVV SKVANFSIDL PSAEVAIQVS
GSFGSRQEEA QRLGRLLRPK TEGRSAHFYT IVSRDTVDAD FAQNRQRFLA EQGYAYRIID
AGDLTAESS
//
