ID A0A0Q9WGU5_DROVI Unreviewed; 2030 AA.
AC A0A0Q9WGU5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Dscam, isoform F {ECO:0000313|EMBL:KRF79696.1};
GN Name=Dvir\Dscam {ECO:0000313|EMBL:KRF79696.1};
GN ORFNames=Dvir_GJ20560 {ECO:0000313|EMBL:KRF79696.1};
OS Drosophila virilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7244 {ECO:0000313|EMBL:KRF79696.1, ECO:0000313|Proteomes:UP000008792};
RN [1] {ECO:0000313|EMBL:KRF79696.1, ECO:0000313|Proteomes:UP000008792}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15010-1051.87 {ECO:0000313|Proteomes:UP000008792};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH940648; KRF79696.1; -; Genomic_DNA.
DR RefSeq; XP_015029368.1; XM_015173882.1.
DR SMR; A0A0Q9WGU5; -.
DR EnsemblMetazoa; FBtr0435037; FBpp0392045; FBgn0082392.
DR Proteomes; UP000008792; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 6.
DR CDD; cd20957; IgC2_3_Dscam; 1.
DR CDD; cd20953; IgI_2_Dscam; 1.
DR CDD; cd20956; IgI_4_Dscam; 1.
DR CDD; cd20958; IgI_5_Dscam; 1.
DR CDD; cd20954; IgI_7_Dscam; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 16.
DR InterPro; IPR021012; Dscam_C.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR10075; BASIGIN RELATED; 1.
DR PANTHER; PTHR10075:SF14; DOWN SYNDROME CELL ADHESION MOLECULE 3, ISOFORM E-RELATED; 1.
DR Pfam; PF12355; Dscam_C; 1.
DR Pfam; PF00041; fn3; 6.
DR Pfam; PF07679; I-set; 5.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00060; FN3; 6.
DR SMART; SM00409; IG; 9.
DR SMART; SM00408; IGc2; 9.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 9.
DR PROSITE; PS50853; FN3; 6.
DR PROSITE; PS50835; IG_LIKE; 10.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000008792};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..2030
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006386780"
FT TRANSMEM 1638..1660
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..136
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 140..235
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 252..345
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 349..428
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 435..529
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 534..620
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 625..723
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 728..820
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 825..917
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 926..1020
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1025..1129
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1130..1226
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1230..1323
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1325..1407
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1415..1508
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1512..1607
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1716..1747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1824..1875
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1891..2030
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1838..1865
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1977..1999
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2000..2030
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2030 AA; 224177 MW; C0491A9141F4F957 CRC64;
MAYMMPNERL KWLTLCAAVA VLATVSSTLA ANPPDADQKG PVFLKEPTNR IDFSNSTGAE
IECKSSGNPM PEIIWVRSDG TAVGDVPGLR QISSDGKLVF PPFRAEDYRQ EVHAQVYACL
ARNQFGSIIS RDVHVRAVVP QSYSVNVMDE SILRGNSAIL KCHIPSFVAD FIVVDSWVED
EEREIYPQAD VTASDGKYLV LPSGELHIRE VGPEDGYKSY QCRTKHRLTG ETRLSATKGR
LVITEPIGSV PPKITNLHDK FQFVQVNLNE DYSMQCPGQA YPVPIVRWYK FIEGTTRKQA
VVLNDRVKQV SGTLIIKDAV VEDSGKYLCV VNNSVGGESV ETVLTVTAPL SAKIDPPTQT
IDFGRPAVFT CQYTGNPIKT VSWMKDGKAI GHSEPVLRIE SVKKEDKGMY QCFVRNDQES
AEASAELKLG GRFDPPVIRQ AFQEETMEPG PSVFLKCVAG GNPTPEISWE LDGKKIANND
RYQVGQYVTV NGDVVSYLNI TSVHANDGGL YKCIAKSKVG VAEHSAKLNV YGLPYIRQME
KKAIVAGETL IVTCPVAGYP IDSIVWERDN RPLPINRKQK VFPNGTLIIE NVERNSDQAT
YTCVAKNQEG YSARGSLEVQ VMVLPQIVPF PYEDVINTGD SIDLFCQIQK GDRPIKVHWS
FERSASDSDA SDSDMLQPQM RTNRISSKTS MLSIQSASPA HTGTYTCIAS NAAGTTRYGV
NLTVNVPPRW ILEPTDKAFA QGSDAKVECK ADGFPKPQVT WKKAVGDTPG EYKDLKKSDN
IRVEEGTLHI DNIQKTNEGY YLCEAINGIG SGLSAVIMVS VQAPPEFTEK LRNQTARRGE
PAVLQCEAKG EKPIGILWNM NNMRLDPKND NRYTIREEIL SAGVMSSLSI KRTERSDSAL
FTCVATNAFG SDDASINMIV QEVPEMPYAL KVLDKSGRSV QLSWAQPYDG NSPLNRYIIE
FKRSRASWDE IDRVMVPGHT TEAQVQKLSP ATTYNIRIVA ENEIGSSQSS EAVTIITAEE
APSGKPQNIK VDPVNQTTLR VMWKPPPRSD WNGEILGYYV GYKLSNTNSS YIFETINFIT
EEGKEHSLEL NNLRVYTQYS VVIQAFNKIG AGPLSDEEKQ FTAEGTPSQP PSDTACTTLT
SQTIRVSWVS PPLESANGVI KTYKVVYAPS EEWYDETKRH YKKTASSDTV LHGLKKYTNY
TMQVLATTAG GDGVRSVPIH CQTEPDVPEA PTDVKALVMG NAAILVSWRP PAQPNGIITQ
YTVYSKAEGA ETETKTQKVP HYQMSFEATE LEKNKPYEFW VTASTTIGEG QQSKSIVAMP
SDQVPAKIAS FDDTFTATFK EDAKMPCLAV GAPQPEITWK IKGVDFSAND RMRLLPDGSL
LIKSVNRQDA GDYSCHAENS IAKDSITHKL IVLAPPQSPH VTLSATTTDA LTVRLKPHEG
DTAPLHGYTL HYKPEFGEWE TAEVSVESQK HNIENLLCGS RYQVYATGFN NIGAGEASDI
LNTRTKGQKP KLPEKPRFIE VSSNSVSLHF KAWKDGGCPM SHFVVESKKR DQLEWNQISN
NVKPDNNYVV LDLEPATWYN LRITAHNSAG FTVAEYDFAT LTVTGGTIAP LDDGTGHGNV
HARIPLPAWM PEWLDLNFMV PLIATVVVVA VGICVVCVAL SRRRADDMRG GQKDVYYDVV
YNQTMGPGAT LDKRRPDLRD ELGYIAPPNR KLPPVPGSNY NTCDRIKRGR GGLRSNHSTW
DPRRNPNLYE ELKAPPVPMH GIGNHYGHAH GAPECQYRHP GMEDEICPYA TFHLLGFREE
MDPTKAMNFQ TFPHQNGHTP VPGHAGTMLP PGHPGHVHSR SGSQSMPRAN RYQRKNSQGG
QSSIYTPAPE YDDPANCAEE DQYRRYTRVN SQGGSLYSGP GPEYDDPANC APEEDQYGSQ
YGGPYGQPYD HYGSRGSMGR RSIGSARNPG NGSPEPPPPP PRNHDMSNSS FNDSKESNEI
SEAECDRDHG PRGNYGEDSN EETKPAQNNS NSNKQMAQDS QPTILWQCNL
//
