ID A0A0Q9WHH8_DROVI Unreviewed; 1525 AA.
AC A0A0Q9WHH8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Uncharacterized protein, isoform B {ECO:0000313|EMBL:KRF84041.1};
GN Name=Dvir\GJ12464 {ECO:0000313|EMBL:KRF84041.1};
GN ORFNames=Dvir_GJ12464 {ECO:0000313|EMBL:KRF84041.1};
OS Drosophila virilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7244 {ECO:0000313|EMBL:KRF84041.1, ECO:0000313|Proteomes:UP000008792};
RN [1] {ECO:0000313|EMBL:KRF84041.1, ECO:0000313|Proteomes:UP000008792}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15010-1051.87 {ECO:0000313|Proteomes:UP000008792};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH940647; KRF84041.1; -; Genomic_DNA.
DR RefSeq; XP_015030919.1; XM_015175433.1.
DR EnsemblMetazoa; FBtr0434323; FBpp0391399; FBgn0199706.
DR GeneID; 6622911; -.
DR OrthoDB; 946033at2759; -.
DR Proteomes; UP000008792; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR InterPro; IPR045838; DEPDC5_CTD.
DR InterPro; IPR027244; IML1.
DR InterPro; IPR048255; IML1_N.
DR PANTHER; PTHR13179; DEP DOMAIN CONTAINING PROTEIN 5; 1.
DR PANTHER; PTHR13179:SF8; GATOR COMPLEX PROTEIN DEPDC5; 1.
DR Pfam; PF19418; DEPDC5_CTD; 1.
DR Pfam; PF12257; IML1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008792}.
FT DOMAIN 101..388
FT /note="Vacuolar membrane-associated protein Iml1 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF12257"
FT DOMAIN 1249..1490
FT /note="DEPDC5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19418"
FT REGION 625..644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1525 AA; 174565 MW; F902C54EC9C9AC86 CRC64;
MKLFKLNTHT RGCNKSYDAD LVLNPQDHPT AKVGDVVEIY APDDENGTHL LLQITELNEQ
SKTGRNVISI ESCIAIAFKM RSYSNVVMRI VNPADVALDS IEITFKDQYM GRSEMWRLKT
YLTNTCVYVN KKIDYNDMQI RCQVYEMWSQ GERVASGVIT DDTKIVFRSS TSMVYLFLQM
SSEMWDFDIH GDLYFEKAVN GFLTELFQKW KKLGCNHEVT IVLFSRTFYA AKSLDEFPAH
MRDCLQQDYK GRYYEDFYRV AIQNERNDDW CTVLAQLRKL FTSYQETVLR YHERQNMRIP
LATNSTATQG NFLEVLNISL NTFEKHYLDR TFDRTGQLSV VITPGVGVFS VDRELTNITK
QRIIDNGVGS DLVCVGEQPL HAVPLLKFHN KDTTLTSADD YSLPHWINLS FYSTNKKIAY
SSFIPRIKLP ILSHVDEADV EENERNFLSC NQSEYIHNSL FDYDAYDEQI FQPLPAQSTC
SLQRVVRAKK TSVPSFETYA YRNNDWENLT PTKIPSLRRK MSDPDIHHGT SGMLATLTDT
TNLSESLASE KNARRAIVSI APIVRPGRAL INPFDPSHVT IKLTSNRRRW THIFPKGPTG
VLIQQHHYQA VPAKAVPAAC YNRQLHHSNS NNNNNNDQEE QYDQLSNHSL LSQSKSFSSQ
NFAMGEDKSD FFKRRNTSLV NAATAANVPN LTATQAKSYL WGATGEQEWT PAITTENATA
TGKHMKPIVE SEHYNFGRSR LEATTEAVGK GKIIIGVDWK SLSIPACLPI TTDYFPDKRS
LHNDYVISDY TLLPDDVNLD YAKSRAVYRK PLSTEEVCKE IVSQRLAQGF QLIVVEEKQP
SASSCCSASG SCAPASNPTT SAVLPLKASC ELNREYLLSI GRIFHKITLS GSVITVTGYR
PRHPYPPINV DYRYRFHAPQ HETYEISGVN FTTEKLENFS WNHMDLYICT RGDVDYPLME
SLKYWRFRMY LLPRESMVNK IVSFGCQRCD IFTDAVVDNT REQIEDFIRL IENVSKLKRQ
ICRKARQHDT PTPRITEKNH NLLNPPQQSI NVRPKPDPSR ISRILPGTDA ATAAASAVVP
RDDQDDGFPV DIKFSANATL AEMFEAMKHP VNGVGFFTQT QSLPSCTFIS YDALMWLKAR
LTNGRHPLDL LEAMRKERMI CHASGDWNQP IVPGFVFYYV VQQDRNAKDY APPLNDYSAF
VNEWLEIELQ GCSFLWHDEP APTNVPNFLR ETPAPQSWRE YCKSKRVCRK SHLEIDVNQK
SDRMEWGHVK HHTVMQPGFA FELVVEWVTS SGPIVSDLIS GWMRKANHCG YQLVSVPADP
MAEPFTEKSD PLRGPIFIPL CVTFLPNGAT LFDEFPEDSR ADRMLFLQEA ILARFGFMPC
VLEEKFTQKK DLPKEYQYVH CTGNMFALIR CASNKFQVES PSRQEANVTR CVYGHTNNTN
VPKKVGFLWS WNHMIPNKKW KALTINNSAD GELFQLKMLK DFREFCSNSD QRLANFWAHS
QELKRKSLKF EYNNNNNNND EPKII
//
