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Database: UniProt
Entry: A0A0Q9WNN5_DROVI
LinkDB: A0A0Q9WNN5_DROVI
Original site: A0A0Q9WNN5_DROVI 
ID   A0A0Q9WNN5_DROVI        Unreviewed;      1406 AA.
AC   A0A0Q9WNN5;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   16-OCT-2019, entry version 17.
DE   SubName: Full=Uncharacterized protein, isoform I {ECO:0000313|EMBL:KRF82671.1};
GN   Name=Dvir\GJ16010 {ECO:0000313|EMBL:KRF82671.1};
GN   ORFNames=Dvir_GJ16010 {ECO:0000313|EMBL:KRF82671.1}, GJ16010
GN   {ECO:0000313|FlyBase:FBgn0203195};
OS   Drosophila virilis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila.
OX   NCBI_TaxID=7244 {ECO:0000313|EMBL:KRF82671.1, ECO:0000313|Proteomes:UP000008792};
RN   [1] {ECO:0000313|EMBL:KRF82671.1, ECO:0000313|Proteomes:UP000008792}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15010-1051.87 {ECO:0000313|Proteomes:UP000008792};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
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DR   EMBL; CH940655; KRF82671.1; -; Genomic_DNA.
DR   RefSeq; XP_015025112.1; XM_015169626.1.
DR   EnsemblMetazoa; FBtr0441723; FBpp0398238; FBgn0203195.
DR   GeneID; 6634549; -.
DR   FlyBase; FBgn0203195; Dvir\GJ16010.
DR   Proteomes; UP000008792; Unassembled WGS sequence.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.10.440; -; 2.
DR   Gene3D; 1.10.555.10; -; 1.
DR   InterPro; IPR002713; FF_domain.
DR   InterPro; IPR036517; FF_domain_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039007; pG1.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR032835; RhoGAP-FF1.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   InterPro; IPR039006; RhoGAP_pG2.
DR   InterPro; IPR001806; Small_GTPase.
DR   Pfam; PF00071; Ras; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   Pfam; PF16512; RhoGAP-FF1; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; SSF48350; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51676; FF; 4.
DR   PROSITE; PS51852; PG1; 1.
DR   PROSITE; PS51853; PG2; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008792};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008792}.
FT   DOMAIN      256    324       FF. {ECO:0000259|PROSITE:PS51676}.
FT   DOMAIN      369    423       FF. {ECO:0000259|PROSITE:PS51676}.
FT   DOMAIN      430    484       FF. {ECO:0000259|PROSITE:PS51676}.
FT   DOMAIN      486    551       FF. {ECO:0000259|PROSITE:PS51676}.
FT   DOMAIN      599    767       PG1 pseudoGTPase. {ECO:0000259|PROSITE:
FT                                PS51852}.
FT   DOMAIN      774    934       PG2 pseudoGTPase. {ECO:0000259|PROSITE:
FT                                PS51853}.
FT   DOMAIN     1194   1397       Rho-GAP. {ECO:0000259|PROSITE:PS50238}.
FT   REGION     1012   1035       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COILED      165    185       {ECO:0000256|SAM:Coils}.
FT   COILED     1146   1191       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1406 AA;  162203 MW;  6AFE3BB7EFB23DC0 CRC64;
     MYNKMRQFNI SVIGLSGTEK DRGQVGVGKS CLCNRFMRPM ADDYFIDHIS VLSQSDFSGR
     IVNNDHFLYW GEVRKTTDEG VEYNFNIIEQ TEFMDDSTFQ AFKVGKMDPY LKRCTATKVF
     SAEKLMYICK NQLGIEKEYE QKVMPDGRLS IDGFVVVFDV SPVPNRSVEK QVEFVQNAIA
     NILKNKKPLV LVTTKNDDAY ELYVREAEKI SQRKDYKSTV QLIETSAHES INIDLAFLML
     AQMIDKVKNR VKIISYQESA KSRKELLDIR SEAVTRLIRN QITDYHILWS QGSKMLSQFR
     EWNEFLNIFG HEAGQKLFRR HMKKLRDDHL NKKLHQYLDK FALALEYLLP DIGALNISDD
     DAWECARNYL QNHIEFEQYF FECPQATWTE LLDMDEAEDE ARIPFDVLET NEAETVFRNY
     LNSVQQDKKK IGWKQQFKML LEESGFVTPG KQLSEVRVLF MGRECFEALS EHDCQQIYDI
     HQDEIIEKSK QNFVELLLEH AQYFLQFKNV DIITQEDVRQ ITDVIQEDSR YKMLDRLDQE
     RRVLLVQHLR FIHCPIRDHC PFFNNCVDNL IEELLSDKSA ANHKTVGGGS VGGWKTTGNG
     SERTLNLLIV GSEHLASDLL NDIRICTGSK GEYIYEKQTY YLNYRIANGD MEAFKAIDVY
     SSGLICVYSN QQSFETLKDN LERTLLCNLE LEDKFENLPI VLVYQPQDLK ENEVEYLRSE
     GMRLSEMLHC DFIDHTQNHQ KYVYDILNIV ILSLKLSEMK SYEPYPSANH TDLRILVCIY
     CGDQYDIENI VQPLLAESTL VKANEHCIIV DVFIGDAKRR VEFILSSYHG TNQYRDELIH
     GYIYIYSAKR RSSLANLNIL AAQNANIPLQ LVAVTESGGV NAFFNNEICQ FLITEGNALA
     DRYKGSFMTF SADQYVKFAF YNPFLKTAWD NKYEVENLHV EESITLDSGE GTLENSVNQM
     PRPPPRHESY MLSNTLGTDG SGSENYEMLP TRSLNSLNEE RDISLDEIYD DNNEKPKHLH
     QNCTESDSCA SSTERRVRQQ NAYYKANKKA ATTKKNKKKK VAIPVQTPRV PPFGAYVSPP
     EIPLHYQRMA AVAAAGEKKK AEAGVVPEFM KSDKSPEYSM VPELTAAGIF GAENLPEYNM
     NAKCMKDFEK LEKRRIKEEA ARLRKLQEKE KEQEKKLKRK LKQNAKGLTE TTEAQFGKLM
     ITSDKDEIPI FLIKCVEFIE KEGLDSEGIY RVPGSRAHVD MLFQRFEEDT NTVIDVLDIP
     VNAVATALKD FFSKRLPPLF SKDIIKELEE IAGSRGVGSS KLNVEVKTDR SCRLIALKSL
     LQKLPPINFA ILKYIFQHFV HVSDNSKLNS MDSKNLAICW WPTLIPIDFT DMGHFEQLRP
     YLEDIVQTMI DQFPYLFCGK DAFVMV
//
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