ID A0A0Q9XEM0_DROMO Unreviewed; 1293 AA.
AC A0A0Q9XEM0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 28-JUN-2023, entry version 33.
DE SubName: Full=Uncharacterized protein, isoform C {ECO:0000313|EMBL:KRG03217.1};
DE SubName: Full=Uncharacterized protein, isoform D {ECO:0000313|EMBL:KRG03218.1};
GN Name=Dmoj\GI10257 {ECO:0000313|EMBL:KRG03218.1};
GN ORFNames=Dmoj_GI10257 {ECO:0000313|EMBL:KRG03218.1};
OS Drosophila mojavensis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7230 {ECO:0000313|EMBL:KRG03218.1, ECO:0000313|Proteomes:UP000009192};
RN [1] {ECO:0000313|EMBL:KRG03218.1, ECO:0000313|Proteomes:UP000009192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSC#15081-1352.22 {ECO:0000313|EMBL:KRG03218.1}, and Tucson
RC 15081-1352.22 {ECO:0000313|Proteomes:UP000009192};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
RN [2] {ECO:0000313|EMBL:KRG03218.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TSC#15081-1352.22 {ECO:0000313|EMBL:KRG03218.1};
RX PubMed=18057021; DOI=10.1093/bioinformatics/btm542;
RA Zimin A.V., Smith D.R., Sutton G., Yorke J.A.;
RT "Assembly reconciliation.";
RL Bioinformatics 24:42-45(2008).
RN [3] {ECO:0000313|EMBL:KRG03218.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TSC#15081-1352.22 {ECO:0000313|EMBL:KRG03218.1};
RG FlyBase;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: Belongs to the milton family.
CC {ECO:0000256|ARBA:ARBA00007007}.
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DR EMBL; CH933807; KRG03217.1; -; Genomic_DNA.
DR EMBL; CH933807; KRG03218.1; -; Genomic_DNA.
DR RefSeq; XP_015020924.1; XM_015165438.1.
DR RefSeq; XP_015020925.1; XM_015165439.1.
DR SMR; A0A0Q9XEM0; -.
DR EnsemblMetazoa; FBtr0428877; FBpp0386384; FBgn0133022.
DR EnsemblMetazoa; FBtr0429014; FBpp0386504; FBgn0133022.
DR GeneID; 6576967; -.
DR InParanoid; A0A0Q9XEM0; -.
DR OrthoDB; 2909788at2759; -.
DR Proteomes; UP000009192; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR InterPro; IPR006933; HAP1_N.
DR InterPro; IPR022154; TRAK1/2_C.
DR PANTHER; PTHR15751; TRAFFICKING KINESIN-BINDING PROTEIN; 1.
DR PANTHER; PTHR15751:SF12; TRAFFICKING KINESIN-BINDING PROTEIN MILT; 1.
DR Pfam; PF04849; HAP1_N; 1.
DR Pfam; PF12448; Milton; 1.
DR SMART; SM01424; HAP1_N; 1.
DR SMART; SM01423; Milton; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000009192}.
FT DOMAIN 50..551
FT /note="HAP1 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01424"
FT DOMAIN 639..822
FT /note="Trafficking kinesin-binding protein C-terminal"
FT /evidence="ECO:0000259|SMART:SM01423"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 232..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 701..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 917..940
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 968..996
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1124..1155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1209..1270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 141..168
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 314..376
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 408..551
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 969..991
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1128..1155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1293 AA; 138381 MW; A06F40E74E7E940D CRC64;
MPLFSNNSAL KSNDLQQQQQ QHKPHLNVKL TTTTTTVALP IIHEFTLEPE DDSDGYQHSF
VAGLEAQQEE QLLSSSMVQH VASNSSLCSL TSNCSSSSSN MSSMSNMSNM SNMSNCSSTS
TISKQPSNAS KHFENTYKLL GKQLESNCQR TADKLQQLDQ QLDSLDSLSS SCASMSAIVN
GTKPPPTRLE LELEAVDRMR VIVQQMKATP QEATTNASAP LLALLHDFAA KGQPRRDSTA
QDDSTPSTPV PSPIAGVLPV EGPNFELPAQ LLQSANSWEL MYYASKNVDG QNCLKVVRSL
LTNKVLCGNR VSQMTRAYDD IEAVTRLLEE KEKDLELTVQ IGKELLTQNN ALEARVSDLE
TDLKASNDDR AQLLHELHKK NELISVLTND ADDATDADTP TMSKSITLDL LQKKVNSLLD
ENKTLKNEAT QLAHQTDEVE EHERRLMADI SAQLNDANSQ FDNLSLELER QREENRLQHE
QIVSLTARLA EAEMRLHQLT QDNDEHLSLL HVTKENQNAL ALELVEFKQR YEEVLALLHS
AQDQLKQQRK RSQPQARSSF LGGLGTNGAA AAVAAESLQS ELMESSLYSE NSLDSGISGD
SQRCADRISR MMSQLPGGMG MAASFGSSSI YGPPPYKRVF DTVRCATKSG NYMDSGNVSM
TQMGAMSMSS SSGPRMASMA YPAGSYYRGS SNSLGLKTLS SESLNSQSDD GYPAQPSGVP
GAPGAKELEA ALKRLTPAEV LARRAMLSYA PAGTYNYDEP PTHGRVGAGA AAGGQPAGLN
LPMGVRTPDS IMSTGSGSSS GLTTHQWRLP EKLQIVKPME GSQTLHHWSR LATPTLSGLL
EERPGVTIRG GRGLDDLGMQ VYTLSDVEED VSDDIGLGKQ FEAPGCTYTY TNSMVMHPDD
GFVNDLSFLS QSQMSSRMAS TSTSRQPSCP ATPRAGMSRK NSCSTFSVNL GLAGMLNERG
IKAVTPSALN TPAGPNFSPT VTPCNSPEGS PPRGQSPEPL FGLLSSGADL IKRKLVGPSE
SQVQRSLSKQ QHQQKVMLSH LERRALRSLN LIEKVESIGL ENIISAQRGR SAGIANRSSS
PLSQLSSCGS ISGESLQSVH TNSNQIVDDI HFDRAQIKGV LHRGLKSPTP QQPATSMGVV
SGGSATTSAY SSEDSDDQGI VLQLKARPQP VAGAGSGGAG ATKAGVAPAA PAASVDVSAT
ASETRVKQMQ RQKSRRNLKN GMAAQRPDLG TIAGAGSGRR VRPDLGKVAD SSASAAGDAK
GSDSESRAAP QSITQAFVGS VSSLLFGRKG GWL
//
