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Database: UniProt
Entry: A0A0Q9XES7_DROMO
LinkDB: A0A0Q9XES7_DROMO
Original site: A0A0Q9XES7_DROMO 
ID   A0A0Q9XES7_DROMO        Unreviewed;      1609 AA.
AC   A0A0Q9XES7;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   11-DEC-2019, entry version 18.
DE   SubName: Full=Uncharacterized protein, isoform C {ECO:0000313|EMBL:KRG06893.1};
GN   Name=Dmoj\GI21536 {ECO:0000313|EMBL:KRG06893.1};
GN   ORFNames=Dmoj_GI21536 {ECO:0000313|EMBL:KRG06893.1};
OS   Drosophila mojavensis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7230 {ECO:0000313|EMBL:KRG06893.1, ECO:0000313|Proteomes:UP000009192};
RN   [1] {ECO:0000313|EMBL:KRG06893.1, ECO:0000313|Proteomes:UP000009192}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15081-1352.22 {ECO:0000313|Proteomes:UP000009192};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA   Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA   Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA   Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA   Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA   Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA   Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA   David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA   Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA   Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA   Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA   Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA   Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA   Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA   Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA   Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA   Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA   Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA   Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA   Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA   McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA   Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA   Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA   Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA   Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA   Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA   Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA   Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA   Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA   Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA   Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA   Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA   Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA   Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA   Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA   Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA   Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA   Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA   Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA   Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA   Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA   Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA   D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA   Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA   Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA   Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA   Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA   Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA   McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA   Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA   Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA   Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA   Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA   Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA   Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA   Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA   Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA   Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA   Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA   Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA   Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
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DR   EMBL; CH933811; KRG06893.1; -; Genomic_DNA.
DR   RefSeq; XP_015016557.1; XM_015161071.1.
DR   SMR; A0A0Q9XES7; -.
DR   EnsemblMetazoa; FBtr0424819; FBpp0382628; FBgn0144266.
DR   GeneID; 6585106; -.
DR   Proteomes; UP000009192; Unassembled WGS sequence.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.10.440; -; 2.
DR   Gene3D; 1.10.555.10; -; 1.
DR   InterPro; IPR002713; FF_domain.
DR   InterPro; IPR036517; FF_domain_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039007; pG1.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR032835; RhoGAP-FF1.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   InterPro; IPR039006; RhoGAP_pG2.
DR   InterPro; IPR001806; Small_GTPase.
DR   Pfam; PF00071; Ras; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   Pfam; PF16512; RhoGAP-FF1; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; SSF48350; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51676; FF; 3.
DR   PROSITE; PS51852; PG1; 1.
DR   PROSITE; PS51853; PG2; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN          252..320
FT                   /note="FF"
FT                   /evidence="ECO:0000259|PROSITE:PS51676"
FT   DOMAIN          426..480
FT                   /note="FF"
FT                   /evidence="ECO:0000259|PROSITE:PS51676"
FT   DOMAIN          482..547
FT                   /note="FF"
FT                   /evidence="ECO:0000259|PROSITE:PS51676"
FT   DOMAIN          597..765
FT                   /note="PG1 pseudoGTPase"
FT                   /evidence="ECO:0000259|PROSITE:PS51852"
FT   DOMAIN          772..932
FT                   /note="PG2 pseudoGTPase"
FT                   /evidence="ECO:0000259|PROSITE:PS51853"
FT   DOMAIN          1397..1600
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   COILED          161..181
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1352..1394
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1609 AA;  184550 MW;  8E530B571C4E02A4 CRC64;
     MRQFNISVIG LSGTEKDRGQ VGVGKSCLCN RFMRPMADDY FIDHISVLSQ SDFSGRIVNN
     DHFLYWGEVR KTTDEGVEYN FNIIEQTEFM DDSTFQAFKV GKMDPYLKRC TATKVFSAEK
     LMYICKNQLG IEKEYEQKVM PDGRLSIDGF VVVFDVSPVP NRSVEKQVEF VQNAIANILK
     NKKPLVLVTT KNDDAYELYV REAEKISQRK DYKSTVQLIE TSAHESINID LAFLMLAQMI
     DKVKNRVKII SYQESAKSRK ELLDIRSEAV TRLIRNQITD YHILWSQGSK MLSQYREWNE
     FLNIFGHEAG QKLFRRHMKK LRDDHLNKKL HQYLDKFALA LEYLLPDISA LNISDDDAWE
     CARNYLQNHI EFDQYFYEFP QVSWTDFLDM DVPDDETRIP FDVLETNEAE TVFRNYLNSV
     QQDKKKIGWK QQFKMLLEES GFVTPGKQLS EVRVLFMGRE CFEALSEHDC QQIYDIHQDE
     IIEKSKQNFV ELLLEHAQYF LQFKNVDIIT QEDVRQITDV IQEDSRYKML DRLDQERRVM
     LVQHLRFIHC PIRDHCPFFN NCVDNLIEEV LADKSATNHK MGGNVGGGGG GWKTTGNGSE
     RTLNLLIVGS EHLASDLLND IRICTGSKGE YIYENQTYYL NYRIANGDME AFKAIDVYSS
     GLICVYSNQQ SFETLKDNLE RTLLCNLELE DKFENLPIVL VYQPQDLKEN EVEYLRSEGM
     RLSEMLHCDF IDHTQNHQKY VYDILNIVIL SLKLSEMKSY EPYPSSNHTD LRILVCIYCG
     DQYDIENIVQ PLLAESTLVK ANEHCIIVDV FIGDAKRRVE FILSSYHGTN QYRDELIHGY
     IYIYSAKRRS SLANLNILAA QNANIPLQLV AVTESGGVNA FFNNEICQFL ITEGNALADR
     YKGSFMTFSA DQYVKFAFYN PFLKIAWDNK YEVENLHVEE SITLDSGEGT LENSVNQMPR
     PPPRHESYML SNTLGTDGSG SENYEMLPTR SLNSLNEERD ISLDEIYDDN NEKPKHLHQR
     FQIFPPPTTP PEPAPPDHQL ITCTYKSQFV SASESSLEEI TSDVSGSKDS LATHDAEWLE
     DKSDARRNAN KNSIWNNFSG STHAYTTGRR HIDSNLNKIR PKGPSQTLKV GEAPSRNCAM
     SSSTFTLPTQ QPGKLNMKNF QLVSDAVAKM NFTSSGSMGE SYLAGCEPGG DKDAKRYDHA
     QLDGEDEDSE ELAEYEQIYE NEADCTESDS CASSTERRVR QQNAYYKANK KAGTTTKKNK
     KKKVAIPVQT PRVPPFGAYV SPPEIPLHYQ RMAAAAAAGE KKKADSSGVP EFMKSDKSPE
     YSMVPELTAV SIFGAENLPE YNMNAKCLKD FEKLEKRRIK EEQARLRKLQ EKEKEQEKKL
     KRKLKQNAKG LTETTEAQFG KLMITSDKDE IPIFLIKCVE FIEKEGLDSE GIYRVPGSRA
     HVDMLFQRFE DDTNTIIDVL DIPVNAVATA LKDFFSKRLP PLFSKDIIKE LEEIAGSRGV
     GSSKLNVEVK TDRSCRLIAL KSLLQKLPPI NFAILKYIFQ HFVHVSDNSK LNSMDSKNLA
     ICWWPTLIPI DFTDMGHFEQ LRPYLEDIVQ TMIDQFPYLF CGKDAFVMV
//
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