ID A0A0Q9Y2Y2_9STAP Unreviewed; 274 AA.
AC A0A0Q9Y2Y2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Pur operon repressor {ECO:0000256|ARBA:ARBA00018449};
GN ORFNames=ACA31_00140 {ECO:0000313|EMBL:KRG11394.1};
OS Staphylococcus sp. NAM3COL9.
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=1667172 {ECO:0000313|EMBL:KRG11394.1, ECO:0000313|Proteomes:UP000051126};
RN [1] {ECO:0000313|EMBL:KRG11394.1, ECO:0000313|Proteomes:UP000051126}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA309 {ECO:0000313|EMBL:KRG11394.1,
RC ECO:0000313|Proteomes:UP000051126};
RA Gaiero J., Nicol R., Habash M.;
RT "Genome sequencing project of Staphylococcus sp. NA309.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC family. {ECO:0000256|ARBA:ARBA00008391}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRG11394.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LGPC01000002; KRG11394.1; -; Genomic_DNA.
DR RefSeq; WP_002508739.1; NZ_LGPC01000002.1.
DR AlphaFoldDB; A0A0Q9Y2Y2; -.
DR GeneID; 69846880; -.
DR PATRIC; fig|1667172.3.peg.22; -.
DR OrthoDB; 4213751at2; -.
DR Proteomes; UP000051126; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0052657; F:guanine phosphoribosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0045982; P:negative regulation of purine nucleobase metabolic process; IEA:InterPro.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR015265; PuR_N.
DR InterPro; IPR010078; PurR_Bsub.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01743; purR_Bsub; 1.
DR PANTHER; PTHR43864; HYPOXANTHINE/GUANINE PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43864:SF2; PUR OPERON REPRESSOR; 1.
DR Pfam; PF00156; Pribosyltran; 1.
DR Pfam; PF09182; PuR_N; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 4..73
FT /note="Bacterial purine repressor N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09182"
FT DOMAIN 113..263
FT /note="Phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00156"
SQ SEQUENCE 274 AA; 30550 MW; AE0AA5A12E20BF42 CRC64;
MRYKRSERIV YMTQYLMNNP NKLIPLTYFV QKFKQAKSSI SEDVQIIKTT FQKEKLGTVI
TTAGASGGVT YKPEMSKEEA SEVIDDVIAQ LQEKNRLLPG GYLFLSDLMG DPTLLNRVGK
LIATLYMDEE LDAIVTIATK GISLANSVAN VLNLPVVVIR KDNKVTEGST VSINYVSGSS
RKIETMVLSK RTLPENSNVL VVDDFMRAGG SINGVMNLMN EFKAHVKGVS VLVESKEVKQ
RLIEDYTSLV RLSDVDEYNQ EFKVEKGNSL TKFS
//
