ID A0A0Q9Y917_9COXI Unreviewed; 283 AA.
AC A0A0Q9Y917;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=DNA topoisomerase 1 {ECO:0000313|EMBL:KRG17244.1};
DE EC=5.99.1.2 {ECO:0000313|EMBL:KRG17244.1};
GN Name=topA_3 {ECO:0000313|EMBL:KRG17244.1};
GN Synonyms=topA_2 {ECO:0000313|EMBL:KRG17486.1};
GN ORFNames=HT99x_03179 {ECO:0000313|EMBL:KRG17486.1}, HT99x_03217
GN {ECO:0000313|EMBL:KRG17244.1};
OS Candidatus Berkiella aquae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC Berkiella.
OX NCBI_TaxID=295108 {ECO:0000313|EMBL:KRG17244.1, ECO:0000313|Proteomes:UP000051497};
RN [1] {ECO:0000313|EMBL:KRG17244.1, ECO:0000313|Proteomes:UP000051497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HT99 {ECO:0000313|EMBL:KRG17244.1,
RC ECO:0000313|Proteomes:UP000051497};
RA Mehari Y.T., Arivett B.A., Farone A.L., Gunderson J.H., Farone M.B.;
RT "Draft Genome Sequences of Two Novel Amoeba-resistant Intranuclear
RT Bacteria, Candidatus Berkiella cookevillensis and Candidatus Berkiella
RT aquae.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRG17244.1}.
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DR EMBL; LKAJ01000036; KRG17244.1; -; Genomic_DNA.
DR EMBL; LKAJ01000028; KRG17486.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0Q9Y917; -.
DR PATRIC; fig|1590043.3.peg.3235; -.
DR Proteomes; UP000051497; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003917; F:DNA topoisomerase type I (single strand cut, ATP-independent) activity; IEA:InterPro.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR Gene3D; 3.30.65.10; Bacterial Topoisomerase I, domain 1; 3.
DR Gene3D; 1.10.460.10; Topoisomerase I, domain 2; 1.
DR InterPro; IPR000380; Topo_IA.
DR InterPro; IPR013497; Topo_IA_cen.
DR InterPro; IPR013824; Topo_IA_cen_sub1.
DR InterPro; IPR023405; Topo_IA_core_domain.
DR InterPro; IPR013498; Topo_IA_Znf.
DR PANTHER; PTHR42785:SF1; DNA TOPOISOMERASE; 1.
DR PANTHER; PTHR42785; DNA TOPOISOMERASE, TYPE IA, CORE; 1.
DR Pfam; PF01131; Topoisom_bac; 1.
DR Pfam; PF01396; zf-C4_Topoisom; 3.
DR SUPFAM; SSF56712; Prokaryotic type I DNA topoisomerase; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 2.
PE 4: Predicted;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:KRG17244.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051497}.
FT DOMAIN 1..79
FT /note="DNA topoisomerase type IA central"
FT /evidence="ECO:0000259|Pfam:PF01131"
FT DOMAIN 108..145
FT /note="DNA topoisomerase type IA zn finger"
FT /evidence="ECO:0000259|Pfam:PF01396"
FT DOMAIN 159..195
FT /note="DNA topoisomerase type IA zn finger"
FT /evidence="ECO:0000259|Pfam:PF01396"
FT DOMAIN 201..238
FT /note="DNA topoisomerase type IA zn finger"
FT /evidence="ECO:0000259|Pfam:PF01396"
SQ SEQUENCE 283 AA; 32620 MW; EDB3002DF98ADFAF CRC64;
MEEYGIGRPS TYATIISTLQ QREYAVLENK RFHPTDVGRV VNRFLTTYFQ QYVDYGFTAQ
LENELDEISL GEKEWRPVLR EFWQPFIDLV KETQENVQRK DVTQEPIDEK CPQCGSALSI
RLGRRGRFIG CTSYPECDYT RSLEDGTSQD AKPEIVEGRL CPTCESPLQI KKGKYGKFIG
CSSYPDCKFI EPLEKPEDTG VECPSCKEGN ILKRKSRQGK IFYSCARYPD CKYALWYQPL
NEPCPLCEWP ITAVKITKKN GTERVCPQQS CKFSEPYDET PPT
//
