ID   A0A0Q9YRA0_9COXI        Unreviewed;      2018 AA.
AC   A0A0Q9YRA0;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN   ORFNames=CC99x_00839 {ECO:0000313|EMBL:KRG19310.1};
OS   Candidatus Berkiella cookevillensis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC   Berkiella.
OX   NCBI_TaxID=437022 {ECO:0000313|EMBL:KRG19310.1, ECO:0000313|Proteomes:UP000051494};
RN   [1] {ECO:0000313|EMBL:KRG19310.1, ECO:0000313|Proteomes:UP000051494}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC99 {ECO:0000313|EMBL:KRG19310.1,
RC   ECO:0000313|Proteomes:UP000051494};
RA   Mehari Y.T., Arivett B.A., Farone A.L., Gunderson J.H., Farone M.B.;
RT   "Draft Genome Sequences of Two Novel Amoeba-resistant Intranuclear
RT   Bacteria, Candidatus Berkiella cookevillensis and Candidatus Berkiella
RT   aquae.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRG19310.1}.
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DR   EMBL; LKHV01000003; KRG19310.1; -; Genomic_DNA.
DR   RefSeq; WP_057623969.1; NZ_LKHV02000001.1.
DR   STRING; 437022.CC99x_00839; -.
DR   PATRIC; fig|1590042.3.peg.855; -.
DR   OrthoDB; 7021815at2; -.
DR   Proteomes; UP000051494; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd07207; Pat_ExoU_VipD_like; 2.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   PANTHER; PTHR46394; ANNEXIN; 1.
DR   PANTHER; PTHR46394:SF1; PNPLA DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01734; Patatin; 2.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 2.
DR   PROSITE; PS51635; PNPLA; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051494}.
FT   DOMAIN          35..288
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|PROSITE:PS51635"
FT   DOMAIN          1223..1487
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|PROSITE:PS51635"
FT   COILED          495..562
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1690..1724
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   2018 AA;  231708 MW;  6FCBD44AAF6BFD93 CRC64;
     MSKTALSIPY IHELFLKYAN IADLHRERSV PIENLVFEGG GVKGLVYAGA IEVLEAENIL
     KGVKRVAGSS AGGITALLLG FGFSVSEIKR IMSDEIDFTQ LMDRRITWDP TRVINLAGMS
     IGITDIVMLF KNKGLYKGDA FVQVVKAILK KKVEENLKTH IQKIYKDKIN ELKDTGSDAE
     IEMFVQGKML ELLDKYYIND LGNITFEQFE KLKSEFPEWN LKSIYLTGTK LSDGSLRVFS
     RDSDPTMSIV DAVRITMSFP FGFEPVLYQG EYYADGGIAD NYPMHIFNAE QFQTHGLNQS
     GVNPCTLGFL VDSKEEIGVR WGKKEPAQNE LSIKKFAGSV LSGIHNRWEI LKDIYNIQSI
     QIDDLGVPTM DLALSAQMKA KLIDSGREPT QFYFDNYYNK KDILSTLPEY EDFLEKYYSK
     GQPELKRIIE TEIWPILNEV HTINIAFNTL PISDLLAEVK NKLNLCDEAI IQNEALRIER
     THKYEHHLET INLQIDNLTT KISLLDSDIR NCQRRIKNLA DIPDERQGQD LSEIYNRLKE
     EKKKYKRKFQ KVESNRNSIL EEVQKEYKQA DNYVFNLLIK EQEYTLFQEN RFIEKLQEIE
     LKLHEQLDLA LDAIHGYQRS YPDPRTSTEY EKNIFLMTQK LHQKYFNTFL NILKYDDIQS
     GENANRCIEL IDAMLKMGYS LEASESVLSF YLRSKKFSGL TDKKMAADIL FKIFVSELEE
     NILLENYLPL NALFEKAMIE HYDVGASIAE SALFAQQRCY EKCVELERIR MAQKWVVTPS
     EDENIYYAES LRKTTRQLSI GKWGDQIVVE NQDCASYNLQ RLNTKDKETY GKMSTNYTVQ
     TITRKEFNNP SIGKDSLPVI AHILTPESLH LKNTSIDQKE IIVAFQASDL ESDKFSVASL
     HSQQRIKQFE ECKEEIINQI LWNIRQSKEI ARPNNSTYKI TIHGEGLAGQ DAQYLLQALL
     DEIKSCSHRE GLMDISKINL VLVDPSRVDV QCALDLKSNI QKLNEYKLMP ELLGYTLINH
     SKIGKENYNR LAQNYIGDAN ILGFLAADEA TVKVDFVDHE RPNIRLQSYS NKESSVDNIV
     NVSNYIYKQA WFRYLYMAGT NIKNIAKAIL VDFMPNVVLS FVKLPFQIGW NILKRFTNPF
     VRIFKRFGRN IELPQKINWL ENKKQSHLNE KKVKKGKFFD KEKFQKELLQ GIAYNEKKIT
     TLLSESTISE RLKQETRPPI ENIVFEGGGV KGIAYVGAIE AMERNGMLKD VKRVAGSSAG
     GITASLVALG YNAEELKNIF INEINFDELM DEPFDLGGID ALFEASGMSV SLSGIVSLFK
     NKGLFKGENF DSLLKKLIHR KLEHKLKEML FNALTEDDLI KIYQPQDPSL LTDEEKNHLI
     DQFLTERLSA FLEKENITNL SEITLGQLKT LRKKYPTLGL LDIILTATDL GDASLKTFSA
     ESDKDLPLHK AVRMTMSFPG GFMPVNYNNR WYADGGIANN YPIEVFDQPK YLSHGRNHAG
     VNPCTLGILI DSQEEIQSRW GIRVESETTL TLPSFIASVL YGMHNRSEIL RDRYNINSIQ
     IIDDIGSEGQ YKPTATMDLN LNIADKLKLY QNGASALDSY HALYMGENVQ YHLVDSYKNL
     EQKYYSKSVK EMKNIFQTEI IPLIQQFEMM LPYLDRWESK VQKEIADNDL SLNNEIESIL
     IKIENRTYQV QALEKDNALF EKNMQILNEK LNASQTAYQH LKSKIDNHTA TESEILLEPT
     LFKEYQKAQD LVAEKSKRRE IFLQKNINLK NEIDGLQKVL IKYNEKDISA VKKLRVLNDY
     IILIQQAREA HAFLLKEKAI LLKAANLKGK DLSEKQEINT TIKKSESDMM HDLFREYYTS
     SESALQFSLY DNGGNHSSSD AKNKYMSQLL NVFNDSQWIE ESDRNSSRFV AMGEKNIFAQ
     IDFTDTTARF SGTAFHELNK AAALYQQTYQ NDELEVDYDI EADTLEDGLA ILKNLNQSGF
     NVNLVKKMYL KSELVVEDDA FEKMKQDVIR DLKNIALR
//