ID A0A0Q9YZ32_9COXI Unreviewed; 624 AA.
AC A0A0Q9YZ32;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Cytochrome c-type biogenesis protein CcmF {ECO:0000313|EMBL:KRG21464.1};
GN Name=ccmF {ECO:0000313|EMBL:KRG21464.1};
GN ORFNames=HT99x_01216 {ECO:0000313|EMBL:KRG21464.1};
OS Candidatus Berkiella aquae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC Berkiella.
OX NCBI_TaxID=295108 {ECO:0000313|EMBL:KRG21464.1, ECO:0000313|Proteomes:UP000051497};
RN [1] {ECO:0000313|EMBL:KRG21464.1, ECO:0000313|Proteomes:UP000051497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HT99 {ECO:0000313|EMBL:KRG21464.1,
RC ECO:0000313|Proteomes:UP000051497};
RA Mehari Y.T., Arivett B.A., Farone A.L., Gunderson J.H., Farone M.B.;
RT "Draft Genome Sequences of Two Novel Amoeba-resistant Intranuclear
RT Bacteria, Candidatus Berkiella cookevillensis and Candidatus Berkiella
RT aquae.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the biogenesis of c-type cytochromes. Possible
CC subunit of a heme lyase. {ECO:0000256|ARBA:ARBA00037230}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC {ECO:0000256|ARBA:ARBA00009186}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRG21464.1}.
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DR EMBL; LKAJ01000004; KRG21464.1; -; Genomic_DNA.
DR RefSeq; WP_075065850.1; NZ_LKAJ02000001.1.
DR AlphaFoldDB; A0A0Q9YZ32; -.
DR STRING; 295108.HT99x_01216; -.
DR PATRIC; fig|1590043.3.peg.1231; -.
DR OrthoDB; 9761451at2; -.
DR Proteomes; UP000051497; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR InterPro; IPR032523; CcmF_C.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR003567; Cyt_c_biogenesis.
DR InterPro; IPR003568; Cyt_c_biogenesis_CcmF.
DR NCBIfam; TIGR00353; nrfE; 1.
DR PANTHER; PTHR43653; CYTOCHROME C ASSEMBLY PROTEIN-RELATED; 1.
DR PANTHER; PTHR43653:SF1; CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMF; 1.
DR Pfam; PF16327; CcmF_C; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR PRINTS; PR01410; CCBIOGENESIS.
DR PRINTS; PR01411; CCMFBIOGNSIS.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytochrome c-type biogenesis {ECO:0000256|ARBA:ARBA00022748};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000051497};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 476..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 600..620
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 83..290
FT /note="Cytochrome c assembly protein"
FT /evidence="ECO:0000259|Pfam:PF01578"
FT DOMAIN 310..617
FT /note="Cytochrome c-type biogenesis protein CcmF C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF16327"
SQ SEQUENCE 624 AA; 69647 MW; E9B49F690972BEB6 CRC64;
MIPELGLFSL ILALGLASIT LVGSFYRPLQ LMQRGATLGF IAFVFFSFIS LVYCFVQDDF
SVAYIAHNSN THLPFMYKVC AVWGGHEGSL LLWLFILSAW TLVVTLLSRS LPEKVLRSLL
GVLAAIHIGF LLLLLHTSNP FLRFLPNIPT DGADLNPLLQ DPGFVMHPPF LYLGYVGFAI
PFAFAIAAML NPRESFAWAK WARPYALMAF SFLTIGISLG SWWAYYELGW GGWWFWDPVE
NASFMPWLVG VALVHALKVS SQKPLFSSWS LLLALCAFAL SLVGTFLVRS GVLSSVHAFA
SDPARGVFIL YFLAAVLISS FGLYLYHLQR SEAAARIQFV SKESFIFLGN IIFVIATATV
LLGTLYPLIM EVISKEKISV GPPYYTMVFV PIMLPMLVLM SLAPYSFWEQ DRFSHIVKRI
KTPLLLGATI FAAVCFLAWH SLPVMSLLGV ILGIMLVVSS LFKLRGPWQL SKMAMILAHV
GLGVSVLGIS LTTALETEKE VQLAVGQTVH LAPYDVEFAT LQDQEGPNYF GKQGHFIIQQ
DKKTLAHLYP EKRFFTAREM MMTETAISAG LFRDFYIALG ERFQDGTWSV RLYIKPFVRW
LWLGGLMVAL GAFLAAITAL QRRV
//
