ID A0A0Q9Z455_9FLAO Unreviewed; 1477 AA.
AC A0A0Q9Z455;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Multidrug transporter AcrB {ECO:0000313|EMBL:KRG27631.1};
GN ORFNames=APR42_11220 {ECO:0000313|EMBL:KRG27631.1};
OS Salegentibacter mishustinae.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Salegentibacter.
OX NCBI_TaxID=270918 {ECO:0000313|EMBL:KRG27631.1, ECO:0000313|Proteomes:UP000051643};
RN [1] {ECO:0000313|EMBL:KRG27631.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 12263 {ECO:0000313|EMBL:KRG27631.1};
RA Lin W., Zheng Q.;
RT "Draft genome sequence of Salegentibacter mishustinae KCTC 12263.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC family. {ECO:0000256|ARBA:ARBA00007613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRG27631.1}.
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DR EMBL; LKTP01000035; KRG27631.1; -; Genomic_DNA.
DR RefSeq; WP_057482981.1; NZ_QKZW01000005.1.
DR STRING; 270918.APR42_11220; -.
DR OrthoDB; 9758757at2; -.
DR Proteomes; UP000051643; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004763; CusA-like.
DR InterPro; IPR003423; OMP_efflux.
DR NCBIfam; TIGR00914; 2A0601; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF24; CATION EFFLUX SYSTEM (ACRB_ACRD_ACRF FAMILY); 1.
DR Pfam; PF00873; ACR_tran; 1.
DR Pfam; PF02321; OEP; 2.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000051643};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 343..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..504
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 547..566
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 888..907
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 914..933
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 939..961
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 987..1006
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1018..1043
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1064..1082
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1477 AA; 165215 MW; DF3A302F5838EE7E CRC64;
MINKIIAFSI NNKFIIGLLT LALIGTGIWS MMTVNLGSVP DITNNQVQVI TQSPNLATED
IEQFVTYPVE LSMGNLPGVT EIRSISRFGL SVVTIVFKDD MGTYLPRQLV QEKLNELGET
IPDKFGSPAM GPISTGLGQI YEYTIKPKEG YETEYSPMEL RTIQDWIIKR QLTLLEGVVE
VNSFGGSIKQ YEVAINPEKL NSMGISISEV YEALARNNVN TGGAYIEKNK MSNFIRGEGL
IRSLEDIRKI AITTENSIPI TIGDVAEDVQ FGNQVRYGAF TQDGEEAVGG IIMMLKGANP
NAVIQDVKDR MAEVEKSLPE GLTIEPIIDR SELIARTTDT VKTNLLEGAL IVIFALVLLL
GSLRGGLITA TTIPLSLLFA FILMKQFNVW ANLMSLGAID FGIIIDGAVI IIEGTVYEIQ
KRIRSGKVKF NQAKMDEVAY DAGSTMMSSA FFGQIIILIV FTPILFLTGV EGKMFKPMAY
TFGFAMIGAI FLCLTYVPMM SALFMKPIQN KKNWFGRFER WLERISDKII GGIQRVYMPL
LKGALKLKLI VVGAAAVLLV LAGFLFSRMG GEFVPQLDEG DIAMQALIRP GSSLTESIEV
SKKIENILLE NFPEIKTATA RIGVADIPTD PMPMDIADMY LILEKDKDNW TTAETKEGLI
AQIKEKLNKE LTGVNLVFTQ PVELRFNELL EGVREDIAVK LYGEDLGVLS EKVQEMANII
QTVPGAGDVN PERTSGLPQM TVKFNRDKIA QYGLDIQKAN DYISTAFAGG TAGVIFEGEK
RFDLVVRFDE EHRKNIDDLR GMYIDLPDGT QVPIKEIADI EYVPGPMQIS RDDTYRRTYV
GVNARGRDVE SVVNDIQQRL DEELELPPGY YITYGGEFEN LQSAKDRLII VVPIALFLIF
VLLYFALKSF SQSVMIYIAI PLAAIGGVFA LWLRGMPFSI SAGVGFIVLF GVAVLNGLVL
INRFNSLKEE GVTSIRDRIF TGTKERIRPI MLTATTDIFG FLPMAFSTSA GAEVQQPLAT
VVIGGMLTAT LLTLVVLPVL YTLVERKREK KEQNKLGSSN SRSLATILII GLVLGGTFSV
NAQSDAMSSE YSQQDSLQTI SLEDAKEMAI KNFPQLQAAQ LEIESEEVLR KTAFDFGNTQ
IFTGKEEVGN GSDGIYTQIG VQQQGIDIFG IVPRLKLQKE RVALAENALE LSTIEIEREV
SRAWTSVYTS KKRYQVYKKM DSIFEDIERA ARIRYETEAT SKLEYLATSN QGNEVKIQLE
QAYRDYLKSI QRLNLWFVSD TIYDVPDLPA EALDEPLNFL VESLENHPLL QVSEQRIDVA
KAVTRERKSE FLPKFQGQYG RQEIAGQSGF FQYQIGIQIP LFFGPELGRT QEAQVNRKIA
EQNFYQDKLE LEIAYKNMRE DYIKWRNSWN YYRDEALPLA QEQQDGSVLA FKEGAIDYVT
FLQNIRDAIR IEVNAWSAFN DYLDSRYQLE YYLKNSN
//
