ID A0A0Q9ZA66_9FLAO Unreviewed; 728 AA.
AC A0A0Q9ZA66;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Ribonuclease R {ECO:0000256|HAMAP-Rule:MF_01895};
DE Short=RNase R {ECO:0000256|HAMAP-Rule:MF_01895};
DE EC=3.1.13.1 {ECO:0000256|HAMAP-Rule:MF_01895};
GN Name=rnr {ECO:0000256|HAMAP-Rule:MF_01895};
GN ORFNames=APR42_14025 {ECO:0000313|EMBL:KRG29887.1};
OS Salegentibacter mishustinae.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Salegentibacter.
OX NCBI_TaxID=270918 {ECO:0000313|EMBL:KRG29887.1, ECO:0000313|Proteomes:UP000051643};
RN [1] {ECO:0000313|EMBL:KRG29887.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 12263 {ECO:0000313|EMBL:KRG29887.1};
RA Lin W., Zheng Q.;
RT "Draft genome sequence of Salegentibacter mishustinae KCTC 12263.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: 3'-5' exoribonuclease that releases 5'-nucleoside
CC monophosphates and is involved in maturation of structured RNAs.
CC {ECO:0000256|HAMAP-Rule:MF_01895}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage in the 3'- to 5'-direction to yield
CC nucleoside 5'-phosphates.; EC=3.1.13.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001849, ECO:0000256|HAMAP-
CC Rule:MF_01895};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|HAMAP-Rule:MF_01895}.
CC -!- SIMILARITY: Belongs to the RNR ribonuclease family. RNase R subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_01895}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRG29887.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LKTP01000003; KRG29887.1; -; Genomic_DNA.
DR RefSeq; WP_057480913.1; NZ_QKZW01000008.1.
DR AlphaFoldDB; A0A0Q9ZA66; -.
DR STRING; 270918.APR42_14025; -.
DR OrthoDB; 9764149at2; -.
DR Proteomes; UP000051643; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008859; F:exoribonuclease II activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016070; P:RNA metabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd04471; S1_RNase_R; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 3.
DR HAMAP; MF_01895; RNase_R; 1.
DR InterPro; IPR011129; CSD.
DR InterPro; IPR040476; CSD2.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR013223; RNase_B_OB_dom.
DR InterPro; IPR001900; RNase_II/R.
DR InterPro; IPR022966; RNase_II/R_CS.
DR InterPro; IPR004476; RNase_II/RNase_R.
DR InterPro; IPR011805; RNase_R.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00358; 3_prime_RNase; 1.
DR NCBIfam; TIGR02063; RNase_R; 1.
DR PANTHER; PTHR23355:SF9; DIS3-LIKE EXONUCLEASE 2; 1.
DR PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR Pfam; PF17876; CSD2; 1.
DR Pfam; PF08206; OB_RNB; 1.
DR Pfam; PF00773; RNB; 1.
DR Pfam; PF00575; S1; 1.
DR SMART; SM00357; CSP; 2.
DR SMART; SM00955; RNB; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 3.
DR PROSITE; PS01175; RIBONUCLEASE_II; 1.
DR PROSITE; PS50126; S1; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01895};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000256|HAMAP-
KW Rule:MF_01895};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_01895};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_01895};
KW Reference proteome {ECO:0000313|Proteomes:UP000051643};
KW RNA-binding {ECO:0000256|HAMAP-Rule:MF_01895}.
FT DOMAIN 642..723
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
SQ SEQUENCE 728 AA; 83655 MW; 9498C34B86C884F0 CRC64;
MSKKNKNKSQ HQSNLSKSIL DILRKDAGKT FNHKQIAAKL GVNDANSRNN IIKKLAQLAA
KKQIEEEGRG KFKIVKSNDY YRAVIDMTTK GYAYAMVDEL EDDVFISPRD LNTAFNGDEV
EIYIYNRKRN KKSEGEVTKI LNRKRTEFVG VLDMQKDFGF VVIGDPKMYT DIFVQKNKMG
EAKDGDKVVV ELEEWPEKAD SPFGKIIQVL GTPGEHHTEI HSILAQYGLP HEFPQEIEDF
ANQIDTSIQP EEIKKRRDMR DVLTFTIDPA DAKDFDDALS FQKLENGNVE VGIHIADVSH
YLQPGTVLDD EAYERATSVY LVDRVVPMLP EVLSNNACSL RPNEEKYTFS AVFEIDKNTK
VVNEWFGRTV TYSDARFAYE EAQQIIETEK GDIPEEISIQ DKAYTVKDEI VEAVLTMNKM
AKKMRATRMR QGAISFDKVE VKFQLDEENE PVGVYFKTAK DANKLIEEFM LLANRKVAEF
IGKRDEKKTF IYRCHDEPDE EKLVSLNSLV SRFGHGLNLK NRKTVSSSLN QLLQDVQGKK
EQNLVDTLAI RTMSKAYYGT ENIGHYGLAF DYYSHFTSPI RRYPDVMVHR LLQRYLDGQP
SAKEDEYEEK CHHSSEMENL SSNAERDSIK YMQVKFMQDH QDKEFIGVIS GVTDFGIFVE
IVENKCEGMI RLRDIKGDHY DFDADNYAIV GRKTKMVYQL GDEVIVKVKN ADLVKRHLDF
TLIGKKEE
//
