ID   A0A0R0C4Z9_9GAMM        Unreviewed;       372 AA.
AC   A0A0R0C4Z9;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE            EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN   ORFNames=ABB26_06740 {ECO:0000313|EMBL:KRG64809.1};
OS   Stenotrophomonas humi.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Stenotrophomonas.
OX   NCBI_TaxID=405444 {ECO:0000313|EMBL:KRG64809.1, ECO:0000313|Proteomes:UP000050864};
RN   [1] {ECO:0000313|EMBL:KRG64809.1, ECO:0000313|Proteomes:UP000050864}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18929 {ECO:0000313|EMBL:KRG64809.1,
RC   ECO:0000313|Proteomes:UP000050864};
RA   Patil P.P., Midha S., Patil P.B.;
RT   "Genome sequencing and analysis of members of genus Stenotrophomonas.";
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC         Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC         Evidence={ECO:0000256|ARBA:ARBA00001524};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRG64809.1}.
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DR   EMBL; LDJI01000012; KRG64809.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0R0C4Z9; -.
DR   STRING; 405444.ABB26_06740; -.
DR   PATRIC; fig|405444.3.peg.351; -.
DR   Proteomes; UP000050864; Unassembled WGS sequence.
DR   CDD; cd03141; GATase1_Hsp31_like; 1.
DR   Gene3D; 3.40.50.880; -; 1.
DR   InterPro; IPR029062; Class_I_gatase-like.
DR   InterPro; IPR002818; DJ-1/PfpI.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR   PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR   Pfam; PF01965; DJ-1_PfpI; 1.
DR   SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..372
FT                   /note="D-lactate dehydratase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5006393531"
FT   DOMAIN          50..245
FT                   /note="DJ-1/PfpI"
FT                   /evidence="ECO:0000259|Pfam:PF01965"
SQ   SEQUENCE   372 AA;  39952 MW;  E15F42444AA34B70 CRC64;
     MSRVLLTASV CLLATSATPL LAAPSTDKVL IVVSGEGKDA GKQRPGYEFD ELSQAWGVFK
     ANGLEVEIAS PKGGPVEADK YNPAEPFNAA LLADKEAMRK LADTQATSTL EADDYAAIYV
     VGGKGAMFDL PRDASLRQLA GRIWDNGGIV AAVCHGPAAL VDVRLADGSL LVNGRKLTGF
     SNEEEALFGK KWAAEFPWLL EDTMRQRGAQ WSEAPLMMPK LVVDGRLITG QNPYSTYAVA
     EAIVRATGRT PVARKPSRDE LSIALVERLL AGDAQGPRDA LATEPGRYHI DLIGILGYYQ
     AQAATDDAAL EQALQVMDLA LPHMHEPQLK LAAAEAHLKL KRPQQARALV LKALETDPKL
     EQAQALLQRI DG
//