ID A0A0R0EDA7_SOYBN Unreviewed; 766 AA.
AC A0A0R0EDA7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN Name=100810400 {ECO:0000313|EnsemblPlants:KRG92127};
GN ORFNames=GLYMA_20G192700 {ECO:0000313|EMBL:KRG92127.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EMBL:KRG92127.1};
RN [1] {ECO:0000313|EMBL:KRG92127.1, ECO:0000313|EnsemblPlants:KRG92127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRG92127};
RC TISSUE=Callus {ECO:0000313|EMBL:KRG92127.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRG92127}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRG92127};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRG92127.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRG92127.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
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DR EMBL; CM000853; KRG92127.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R0EDA7; -.
DR SMR; A0A0R0EDA7; -.
DR STRING; 3847.A0A0R0EDA7; -.
DR EnsemblPlants; KRG92127; KRG92127; GLYMA_20G192700.
DR Gramene; KRG92127; KRG92127; GLYMA_20G192700.
DR InParanoid; A0A0R0EDA7; -.
DR Proteomes; UP000008827; Chromosome 20.
DR ExpressionAtlas; A0A0R0EDA7; baseline and differential.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0031559; F:oxidosqualene cyclase activity; IEA:UniProt.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11764:SF19; TERPENE CYCLASE_MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|RuleBase:RU362003};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 112..369
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 425..760
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 766 AA; 87733 MW; 1948DF94A4919F6F CRC64;
MECYKVIGQR NMWKLKIAEG GKGLISVNDF IGRQHWIFDP NAGTPQERAE VERLRHQFTK
NRFSIKQSAD LLMRMQLTKE NQCGPIPPAV KVRDTENITM EDMITTIRRG ISFYSSIQAH
DGHWPAESAG PLFFLQPLVM ALYITGSLDV VLGPEHKKEI VRYLYNHQNE DGGWGFHIEG
HSSMFGSALS YIALRILGEG SQDGEERAMD RARKWILDHG GLVAIPSWGK FWVTVLGVYE
WSGCNPLPPE FWLLPKCSPI HPGKMLCYCR LVYMPMSYLY GKKFVGPITS LIRSLREEVY
NEPYDQINWN KARNIVAKED LYYPHPMIQD MLWGFLHHVG ERVMNCWPFS MLRQKALEIA
INHVRYEDEN SRYLCIGSVE KVLCLIARWV EDPNSEAYKL HLARIPDYFW LAEDGLKIQS
FGCQMWDAAF AIQAILACNV SEEYGPTLRK AHSFVKASQV RENPSGDFKA MYRHISKGSW
TFSMHDHGWQ VSDCTAEGLK AALLLSEMAT DLVGEEMEAE RLYDAVNVIL SLQSSNGGFP
AWEPQRAYRW LEKFNPTEFF EDTLIEMEYV ECTGSAMQGL ALFRKLYPKH RRKEIDHCIS
NAIHYIENTQ NPDGSWYGCW GICYTYGTWF AVVGLTACGK NYHNSPSLRK ACKFLLSKQL
PNGGWGESYL SSQNKVYTNL EGNRANLVQT SWALLSLIDA GQAEIDPTPI HRGIKLLINS
QMEDGDFPQQ EITGVFMRNC TLNYSSYRNI FPIWALGEYR CRVLCG
//
