ID A0A0R0FVM5_SOYBN Unreviewed; 561 AA.
AC A0A0R0FVM5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=aspartate kinase {ECO:0000256|ARBA:ARBA00013059};
DE EC=2.7.2.4 {ECO:0000256|ARBA:ARBA00013059};
GN Name=100803204 {ECO:0000313|EnsemblPlants:KRH06839};
GN ORFNames=GLYMA_16G049300 {ECO:0000313|EMBL:KRH06840.1};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847 {ECO:0000313|EMBL:KRH06840.1};
RN [1] {ECO:0000313|EMBL:KRH06840.1, ECO:0000313|EnsemblPlants:KRH06839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82 {ECO:0000313|EnsemblPlants:KRH06839};
RC TISSUE=Callus {ECO:0000313|EMBL:KRH06840.1};
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
RN [2] {ECO:0000313|EnsemblPlants:KRH06839}
RP IDENTIFICATION.
RC STRAIN=Williams 82 {ECO:0000313|EnsemblPlants:KRH06839};
RG EnsemblPlants;
RL Submitted (FEB-2018) to UniProtKB.
RN [3] {ECO:0000313|EMBL:KRH06840.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Callus {ECO:0000313|EMBL:KRH06840.1};
RA Schmutz J., Cannon S., Schlueter J., Ma J., Mitros T., Nelson W., Hyten D.,
RA Song Q., Thelen J., Cheng J., Xu D., Hellsten U., May G., Yu Y.,
RA Sakurai T., Umezawa T., Bhattacharyya M., Sandhu D., Valliyodan B.,
RA Lindquist E., Peto M., Grant D., Shu S., Goodstein D., Barry K.,
RA Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N., Joshi T.,
RA Libault M., Sethuraman A., Zhang X., Shinozaki K., Nguyen H., Wing R.,
RA Cregan P., Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.,
RA Jackson S.;
RT "WGS assembly of Glycine max.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-aspartate = 4-phospho-L-aspartate + ADP;
CC Xref=Rhea:RHEA:23776, ChEBI:CHEBI:29991, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:57535, ChEBI:CHEBI:456216; EC=2.7.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000709};
CC -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.
CC {ECO:0000256|RuleBase:RU004249}.
CC -!- PATHWAY: Amino-acid biosynthesis; L-methionine biosynthesis via de novo
CC pathway; L-homoserine from L-aspartate: step 1/3.
CC {ECO:0000256|RuleBase:RU004249}.
CC -!- PATHWAY: Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine
CC from L-aspartate: step 1/5. {ECO:0000256|RuleBase:RU004249}.
CC -!- SIMILARITY: Belongs to the aspartokinase family.
CC {ECO:0000256|ARBA:ARBA00010122}.
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DR EMBL; CM000849; KRH06839.1; -; Genomic_DNA.
DR EMBL; CM000849; KRH06840.1; -; Genomic_DNA.
DR RefSeq; XP_014624687.1; XM_014769201.1.
DR RefSeq; XP_014624688.1; XM_014769202.1.
DR AlphaFoldDB; A0A0R0FVM5; -.
DR SMR; A0A0R0FVM5; -.
DR STRING; 3847.A0A0R0FVM5; -.
DR EnsemblPlants; KRH06839; KRH06839; GLYMA_16G049300.
DR EnsemblPlants; KRH06840; KRH06840; GLYMA_16G049300.
DR GeneID; 100803204; -.
DR Gramene; KRH06839; KRH06839; GLYMA_16G049300.
DR Gramene; KRH06840; KRH06840; GLYMA_16G049300.
DR KEGG; gmx:100803204; -.
DR InParanoid; A0A0R0FVM5; -.
DR OMA; IIQSQRC; -.
DR OrthoDB; 2608453at2759; -.
DR UniPathway; UPA00034; UER00015.
DR UniPathway; UPA00050; UER00461.
DR UniPathway; UPA00051; UER00462.
DR Proteomes; UP000008827; Chromosome 16.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0004072; F:aspartate kinase activity; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0009090; P:homoserine biosynthetic process; IBA:GO_Central.
DR GO; GO:0009089; P:lysine biosynthetic process via diaminopimelate; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd04244; AAK_AK-LysC-like; 1.
DR CDD; cd04933; ACT_AK1-AT_1; 1.
DR CDD; cd04918; ACT_AK1-AT_2; 1.
DR Gene3D; 3.30.70.260; -; 2.
DR Gene3D; 3.40.1160.10; Acetylglutamate kinase-like; 1.
DR Gene3D; 1.20.120.1320; Aspartokinase, catalytic domain; 1.
DR InterPro; IPR036393; AceGlu_kinase-like_sf.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR041746; AK-LysC-like.
DR InterPro; IPR047896; AK1_ACT_1.
DR InterPro; IPR047895; AK1_ACT_2.
DR InterPro; IPR001048; Asp/Glu/Uridylate_kinase.
DR InterPro; IPR001341; Asp_kinase.
DR InterPro; IPR042199; AsparK_Bifunc_asparK/hSer_DH.
DR InterPro; IPR018042; Aspartate_kinase_CS.
DR NCBIfam; TIGR00657; asp_kinases; 1.
DR PANTHER; PTHR21499; ASPARTATE KINASE; 1.
DR PANTHER; PTHR21499:SF55; ASPARTOKINASE; 1.
DR Pfam; PF00696; AA_kinase; 1.
DR SUPFAM; SSF55021; ACT-like; 2.
DR SUPFAM; SSF53633; Carbamate kinase-like; 1.
DR PROSITE; PS51671; ACT; 1.
DR PROSITE; PS00324; ASPARTOKINASE; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|RuleBase:RU004249};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008827};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 402..480
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
FT COILED 161..191
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 561 AA; 61451 MW; 9C3E61AFFB7CB6C6 CRC64;
MTSTMQLTMV KGTIPVALSR RVCCQCQASL WPPWRIGFFA PVPLVRRVSS ERVATLRVSC
IKATESDVVE GESGGFADIE TSYTCVMKFG GSSVANAERM REVANLILSF PEERPIIVLS
AMGKTTNMLL LAGEKAVSCG VTMADSIDEL SIIKDLHLRT VEELGVDRNA IEKHLEELEQ
LLKGIAMMKE LTPRTQDYLV SFGECMSTRI FAAYLNTLGI RARQYDAFEM GIITSDDFTN
ADILEATYPA VAKRLHSDWV CDPAIPIVTG FLGKARKSCA VTTLGRGGSD LTATTIGKAL
GLPEIQVWKD VDGVLTCDPN ICPQAKPVPY LTFDEAAELA YFGAQVLHPQ SMRPARESDI
PVRVKNSYNP KAPGTLIAKT RDMSKALLTS IVLKRNVTML DIVSTRMLGQ FGFLAKVFSI
FEELGISVDV VATSEVSISL TLDPSKLWSR ELIQQELDYV VEELEKIAVV NLLKTRSIIS
LIGNVQRSSL ILEKAFHVLR TLGVTVQMIS QGASKVNISL VVNDSEAEQC VRALHKAFFE
SELFELENEC IPGNGSVPAL S
//
