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Database: UniProt
Entry: A0A0R0LJE7_9PROT
LinkDB: A0A0R0LJE7_9PROT
Original site: A0A0R0LJE7_9PROT 
ID   A0A0R0LJE7_9PROT        Unreviewed;       357 AA.
AC   A0A0R0LJE7;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   08-MAY-2019, entry version 15.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   Name=aroG {ECO:0000313|EMBL:KRH78860.1};
GN   ORFNames=FERRO_18580 {ECO:0000313|EMBL:KRH78860.1};
OS   Ferrovum sp. JA12.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Ferrovales; Ferrovaceae;
OC   Ferrovum.
OX   NCBI_TaxID=1356299 {ECO:0000313|EMBL:KRH78860.1, ECO:0000313|Proteomes:UP000050960};
RN   [1] {ECO:0000313|EMBL:KRH78860.1, ECO:0000313|Proteomes:UP000050960}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JA12 {ECO:0000313|EMBL:KRH78860.1,
RC   ECO:0000313|Proteomes:UP000050960};
RA   Poehlein A., Ullrich S.R., Tischler J.S., Schloemann M., Muehling M.,
RA   Daniel R.;
RT   "Genome sequence of the acidophilic iron oxidising Ferrovum strain
RT   JA12.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KRH78860.1}.
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DR   EMBL; LJWX01000002; KRH78860.1; -; Genomic_DNA.
DR   RefSeq; WP_056930537.1; NZ_LJWX01000002.1.
DR   EnsemblBacteria; KRH78860; KRH78860; FERRO_18580.
DR   PATRIC; fig|1356299.4.peg.1866; -.
DR   OrthoDB; 853329at2; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000050960; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000050960};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:KRH78860.1}.
FT   DOMAIN       41    341       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   357 AA;  39393 MW;  FAA972C85DDB3A45 CRC64;
     MNTDHLFKTD DLRIREIKEL SPPAHLLREF PISENASTVV SSTRQQIHHI LQNDDDRLLV
     IVGPCSIHDP VAAMEYASML KPLKEKYASE LLIVMRVYFE KPRTTVGWKG LINDPYLDGT
     FQINEGLKLA RGLLLEINEM GMPAGTEFLD LITPQYFADL ISWGAIGART TESQVHRELA
     SGLSCPVGFK NGTDGNLKIA IDAIRAAQQP HHFLSVTKAG HSAIVATNGN EDCHVILRGG
     KSTNYDAESI EMANAELVKA GLSAKVMIDF SHANSQKDPQ KQLIVSENVA NQIIQGEKRI
     MGVMIESHIV GGRQDLESGK SLTYGQSITD ACVSFADTET ILDHLALSIR LRRQNNR
//
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