ID A0A0R1HRN5_9LACO Unreviewed; 1184 AA.
AC A0A0R1HRN5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Chromosome partition protein Smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN Name=smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN ORFNames=FC96_GL000220 {ECO:0000313|EMBL:KRK49296.1};
OS Secundilactobacillus kimchicus JCM 15530.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Secundilactobacillus.
OX NCBI_TaxID=1302272 {ECO:0000313|EMBL:KRK49296.1, ECO:0000313|Proteomes:UP000050911};
RN [1] {ECO:0000313|EMBL:KRK49296.1, ECO:0000313|Proteomes:UP000050911}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15530 {ECO:0000313|EMBL:KRK49296.1,
RC ECO:0000313|Proteomes:UP000050911};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- FUNCTION: Required for chromosome condensation and partitioning.
CC {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC each terminus and a third globular domain forming a flexible hinge near
CC the middle of the molecule. These domains are separated by coiled-coil
CC structures. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005917}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRK49296.1}.
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DR EMBL; AZCX01000001; KRK49296.1; -; Genomic_DNA.
DR RefSeq; WP_056941683.1; NZ_AZCX01000001.1.
DR AlphaFoldDB; A0A0R1HRN5; -.
DR STRING; 1302272.FC96_GL000220; -.
DR PATRIC; fig|1302272.5.peg.217; -.
DR OrthoDB; 9808768at2; -.
DR Proteomes; UP000050911; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR CDD; cd03278; ABC_SMC_barmotin; 2.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01894; Smc_prok; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR InterPro; IPR011890; SMC_prok.
DR NCBIfam; TIGR02168; SMC_prok_B; 1.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 2.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|HAMAP-
KW Rule:MF_01894};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01894};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_01894}; Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Reference proteome {ECO:0000313|Proteomes:UP000050911}.
FT DOMAIN 519..640
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT COILED 255..373
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 407..475
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 826..923
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 993..1027
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT BINDING 32..39
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
SQ SEQUENCE 1184 AA; 132099 MW; FCE048CE09B7A4FA CRC64;
MKLKSLEISG FKSFADYTKI EFEDGVTGIV GPNGSGKSNV TEAIKWVLGE QSAKNLRGAK
MPDVIFAGTS KRRPLNRAMV TMILDNSDHY VESDYTEVSV TRKLFRNGDS RYELNGQECR
LKDITDLFSD SGIGGNAFSM ISQGRVEAIF NSKPEDRRFI IEEVTGVSKY KSDKEKAKRE
LEQTAGYLNR VNDLVVELEA QLEPLAQESS LATDYVAQKR DFDQLDQTRL VLQIQDQKKA
LKTGQETLAA KQAQIDRSKA ALADHHQALT ELKERQANLQ TQKDELQNQL LDLTKRHQEL
VGQQALTQER QNHRQETIAN LTDRVKTVSD QRDGLTKQLA QCQATLKKEQ QALTAAKERV
KQLAQQLAAL DTTAVSKEID HLQDDYIKAM QDLTSVHNQK AYLQKNQHRA DSESDRANEQ
LQALKQELAT QTAKLQECQQ LVDQAQTALE TAKMRQTAAQ TNRQLRQQKA NQLNQQWLKA
LEVSQRAKAR AKSLEEVAEN YAGFYQGTRA VLKARNQLNG IIGPVAELLQ VDSRYTKAVE
AAIGSQQQNV VVETENAGKA AIQYLNQNRL GRSTFLPLTT IRAKSVDRQT QNLVSQLPGF
LGVGSTLVTI AGDARMRILG DYLLGNVLFI DTLDHAVAIG KQLRQRYRMI TLDGDIISAT
GAMTGGRSKR DSAGLLTQQQ ELSTLKTSIK QMDDQLTEKK RALDQLRQDD DQAALDRLNQ
ALTTASTTYQ KRLNQSELIE QTINTLKRQI KAQTTQQALQ GDEEDFQQAL ADNERAEGEL
NAQVAQMTAA MTAAKAQLTE NQTKSGSVSV ALQTEKETVA AKRVSVGQLQ RDVTEAQTQI
QVADDQLSDF KNQLQDLTAT TTNTSASATS SKQQLAVLAD KQHEVESAIQ QNQAALADQA
AKISELERTV QLATETYNIE QNEKQQAEFA QSRLTTKLDQ SLTTLSEQYH VSLELAVQQA
VDLPLATIQQ RLKLLRRGLE DIGDVNVGSI ETYKQVKERY DFLTQQQADL NEAKQKLLTT
MAEMDQEVIT RFEKAFNLVN AQFQKTFKQM FGGGRGRLEL TDPEHLLTSG IEIMAEPPGK
RLQSMRLLSG GERALTAITL LFAIIQVQPV PYCVLDEAEA ALDPANTARF ASYLNRFQDD
TQFIVITHRK ETMVQTDRLY GITMQESGIS KLVAVDLTKT AEIN
//
