ID A0A0R1L1H2_9LACO Unreviewed; 152 AA.
AC A0A0R1L1H2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Diadenosine tetraphosphate (Ap4A) hydrolase {ECO:0000313|EMBL:KRK89711.1};
GN ORFNames=FC99_GL000263 {ECO:0000313|EMBL:KRK89711.1};
OS Levilactobacillus koreensis JCM 16448.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Levilactobacillus.
OX NCBI_TaxID=1423819 {ECO:0000313|EMBL:KRK89711.1, ECO:0000313|Proteomes:UP000050910};
RN [1] {ECO:0000313|EMBL:KRK89711.1, ECO:0000313|Proteomes:UP000050910}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 16448 {ECO:0000313|EMBL:KRK89711.1,
RC ECO:0000313|Proteomes:UP000050910};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRK89711.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AZDP01000060; KRK89711.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R1L1H2; -.
DR STRING; 637971.ABN16_11120; -.
DR PATRIC; fig|1423819.3.peg.281; -.
DR Proteomes; UP000050910; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd01277; HINT_subgroup; 1.
DR Gene3D; 3.30.428.10; HIT-like; 1.
DR InterPro; IPR039384; HINT.
DR InterPro; IPR019808; Histidine_triad_CS.
DR InterPro; IPR001310; Histidine_triad_HIT.
DR InterPro; IPR011146; HIT-like.
DR InterPro; IPR036265; HIT-like_sf.
DR PANTHER; PTHR46648:SF1; ADENOSINE 5'-MONOPHOSPHORAMIDASE HNT1; 1.
DR PANTHER; PTHR46648; HIT FAMILY PROTEIN 1; 1.
DR Pfam; PF01230; HIT; 1.
DR PRINTS; PR00332; HISTRIAD.
DR SUPFAM; SSF54197; HIT-like; 1.
DR PROSITE; PS00892; HIT_1; 1.
DR PROSITE; PS51084; HIT_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:KRK89711.1}.
FT DOMAIN 15..125
FT /note="HIT"
FT /evidence="ECO:0000259|PROSITE:PS51084"
FT MOTIF 108..112
FT /note="Histidine triad motif"
FT /evidence="ECO:0000256|PIRSR:PIRSR601310-3,
FT ECO:0000256|PROSITE-ProRule:PRU00464"
FT ACT_SITE 110
FT /note="Tele-AMP-histidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR601310-1"
SQ SEQUENCE 152 AA; 17044 MW; B49985986FEEA91C CRC64;
MDQMTLEPHY ADDCVFCKIL KGEIPSYTVY EDNIVKAFLD ISQGTPGHTL VIPKTHVQDI
FAYDADLAAA VFSRIPKIAR AIQAADPTIT GMNIVNNNGK VAYQSVFHSH FHLVPRYTDH
DDFKMIFQDN SGNYTPAKYA AIQEQIKAHL EA
//
