ID A0A0R1L5R3_9LACO Unreviewed; 518 AA.
AC A0A0R1L5R3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Citrate lyase alpha chain {ECO:0000256|PIRNR:PIRNR009451};
DE Short=Citrase alpha chain {ECO:0000256|PIRNR:PIRNR009451};
DE EC=2.8.3.10 {ECO:0000256|PIRNR:PIRNR009451};
DE EC=4.1.3.6 {ECO:0000256|PIRNR:PIRNR009451};
DE AltName: Full=Citrate (pro-3S)-lyase alpha chain {ECO:0000256|PIRNR:PIRNR009451};
DE AltName: Full=Citrate CoA-transferase subunit {ECO:0000256|PIRNR:PIRNR009451};
GN ORFNames=FC99_GL000667 {ECO:0000313|EMBL:KRK88177.1};
OS Levilactobacillus koreensis JCM 16448.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Levilactobacillus.
OX NCBI_TaxID=1423819 {ECO:0000313|EMBL:KRK88177.1, ECO:0000313|Proteomes:UP000050910};
RN [1] {ECO:0000313|EMBL:KRK88177.1, ECO:0000313|Proteomes:UP000050910}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 16448 {ECO:0000313|EMBL:KRK88177.1,
RC ECO:0000313|Proteomes:UP000050910};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + citrate = (3S)-citryl-CoA + acetate;
CC Xref=Rhea:RHEA:19405, ChEBI:CHEBI:16947, ChEBI:CHEBI:30089,
CC ChEBI:CHEBI:57288, ChEBI:CHEBI:57321; EC=2.8.3.10;
CC Evidence={ECO:0000256|PIRNR:PIRNR009451};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=citrate = acetate + oxaloacetate; Xref=Rhea:RHEA:10760,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:30089; EC=4.1.3.6;
CC Evidence={ECO:0000256|PIRNR:PIRNR009451};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR009451}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRK88177.1}.
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DR EMBL; AZDP01000076; KRK88177.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R1L5R3; -.
DR STRING; 637971.ABN16_02865; -.
DR PATRIC; fig|1423819.3.peg.724; -.
DR Proteomes; UP000050910; Unassembled WGS sequence.
DR GO; GO:0009346; C:ATP-independent citrate lyase complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008815; F:citrate (pro-3S)-lyase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008814; F:citrate CoA-transferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 2.
DR InterPro; IPR006472; Citrate_lyase_asu.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR NCBIfam; TIGR01584; citF; 1.
DR PANTHER; PTHR40596; CITRATE LYASE ALPHA CHAIN; 1.
DR PANTHER; PTHR40596:SF1; CITRATE LYASE ALPHA CHAIN; 1.
DR Pfam; PF04223; CitF; 1.
DR PIRSF; PIRSF009451; Citrt_lyas_alpha; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR009451};
KW Lyase {ECO:0000256|PIRNR:PIRNR009451, ECO:0000313|EMBL:KRK88177.1};
KW Transferase {ECO:0000256|PIRNR:PIRNR009451}.
SQ SEQUENCE 518 AA; 56011 MW; 418E59A08E3B31D5 CRC64;
MRRVIILKSK VNRELPDDLM NKLDYKPFET TEIGHPEIQR VAPKVHVSTG DDKIVDSIKQ
VVADTVKDGM TISFHHHFRN GDFVFNQVMR VIIDAGIKNL TLAPSSLTGV MNDMVIEAIK
AGTITNITSS GMRGSLGDFV SHGGLKNPVI FRSHGNRARA IEHGDIKIDV AFLGVPSADR
LGNANGMEGN AVFGSLGYAL MDAQYADQVV LLTDNIVDYP NTPASIKQTQ VDYVVKVDKV
GDPDKIGSGA TRFTKDPKEL KIASMVNDVI THSPYFKDGF SFQTGSGGAA LAVTRYLRQS
MIDNQIKASF ALGGITKPTT DLLNEGLVKK VMDVQDFDKG AADSMHTNGN QQEIDASWYA
DPDNKGAMVD QLDVVILSAL EIDTKFNVNV MTGSDGVIRG AIGGHQDAAT GKLTIISAPL
VRGRIATVVP DVTTVVTPGD SVDVLVTEFG IAINPKRTDL IAALSNIPGL PVYKIEDLQK
MAEKRVGTPK PLEYTDRTVA MIEYRDGTVI DTVKEVKD
//
