ID A0A0R1MUA7_9LACO Unreviewed; 550 AA.
AC A0A0R1MUA7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Drug Na(+) antiporter (Drug efflux pump) {ECO:0000313|EMBL:KRL08442.1};
GN ORFNames=FD09_GL001634 {ECO:0000313|EMBL:KRL08442.1};
OS Schleiferilactobacillus perolens DSM 12744.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Schleiferilactobacillus.
OX NCBI_TaxID=1423792 {ECO:0000313|EMBL:KRL08442.1, ECO:0000313|Proteomes:UP000051330};
RN [1] {ECO:0000313|EMBL:KRL08442.1, ECO:0000313|Proteomes:UP000051330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12744 {ECO:0000313|EMBL:KRL08442.1,
RC ECO:0000313|Proteomes:UP000051330};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRL08442.1}.
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DR EMBL; AZEC01000023; KRL08442.1; -; Genomic_DNA.
DR RefSeq; WP_057822448.1; NZ_AZEC01000023.1.
DR AlphaFoldDB; A0A0R1MUA7; -.
DR STRING; 1423792.FD09_GL001634; -.
DR PATRIC; fig|1423792.3.peg.1654; -.
DR Proteomes; UP000051330; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd13124; MATE_SpoVB_like; 1.
DR InterPro; IPR024923; PG_synth_SpoVB.
DR InterPro; IPR029303; Polysacc_synt_C.
DR InterPro; IPR002797; Polysacc_synth.
DR PANTHER; PTHR30250:SF21; LIPID II FLIPPASE MURJ; 1.
DR PANTHER; PTHR30250; PST FAMILY PREDICTED COLANIC ACID TRANSPORTER; 1.
DR Pfam; PF01943; Polysacc_synt; 1.
DR Pfam; PF14667; Polysacc_synt_C; 1.
DR PIRSF; PIRSF038958; PG_synth_SpoVB; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 22..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 472..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 506..527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 383..530
FT /note="Polysaccharide biosynthesis protein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14667"
SQ SEQUENCE 550 AA; 61473 MW; FA946CD8257A8B6D CRC64;
MSEEKQSAPV QRQNAANTDR KSLVVGSAWM TAGSIISRVL GAIYVIPWGI WMGSHFHSAN
ALFGRGYNIY SIFIIISTVG IPGAISKQIS HYNSLNEYGV SRRLFYQGLI LMSSMGFVAA
AILYFGAPIL GAGDPRMTPI LQSLSWPLIL IPPLSILRGY FQGFSEMAPS AISQLLEQVA
RLVYILGSTF VIMKMIGGNY VTAVAHSTFA AFIGAAVGLI YLVYLYMRQT PRMNEAIAQS
DQNLSVSTRQ IITDIMRQAA PFIILDASVS LYQMFDQYTF NPFMDIFYKL TRAENDYWYQ
LFGFNSNKLI MIIVSLATSM AITVVPILSS ALARRDMQSV REQINNTLEL FFFVMLPSSL
GMAAVSQPLN TVFYRYDPWG TMVLQFNSYI AIIIGLFTVL AAILQGVYLN KQAIRYLLYG
AVFKISLQYS FIYFFGVFGP LATTAVGFFV SSVFMLALLY REFHFRMGDL IVHTTQILVF
STIMFAVVYI AVYLMNFCFS SYDRVLAMVE LVVAAGAGAA IYGYLVLHFR VADRLLGARV
AGIRRRLHMK
//
