ID A0A0R1P7D1_9LACO Unreviewed; 429 AA.
AC A0A0R1P7D1;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Amino acid permease {ECO:0000313|EMBL:KRL28287.1};
GN ORFNames=FC94_GL000578 {ECO:0000313|EMBL:KRL28287.1};
OS Lactobacillus kefiranofaciens subsp. kefirgranum DSM 10550 = JCM 8572.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=1423828 {ECO:0000313|EMBL:KRL28287.1, ECO:0000313|Proteomes:UP000051071};
RN [1] {ECO:0000313|EMBL:KRL28287.1, ECO:0000313|Proteomes:UP000051071}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10550 {ECO:0000313|EMBL:KRL28287.1,
RC ECO:0000313|Proteomes:UP000051071};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRL28287.1}.
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DR EMBL; AZEM01000091; KRL28287.1; -; Genomic_DNA.
DR RefSeq; WP_013855054.1; NZ_AZEM01000091.1.
DR AlphaFoldDB; A0A0R1P7D1; -.
DR GeneID; 72687824; -.
DR PATRIC; fig|1423828.4.peg.599; -.
DR Proteomes; UP000051071; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR004840; Amoino_acid_permease_CS.
DR PANTHER; PTHR43495:SF2; D-SERINE_D-ALANINE_GLYCINE TRANSPORTER; 1.
DR PANTHER; PTHR43495; GABA PERMEASE; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
DR PROSITE; PS00218; AMINO_ACID_PERMEASE_1; 1.
PE 4: Predicted;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 29..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..428
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
SQ SEQUENCE 429 AA; 46694 MW; FBADD9393207DE25 CRC64;
MIAIGGAIGT GLFLGSGSAI HSAGPSIILS YLIVGIITFF MMRALGELIL ADPESRSFLE
AIKKYLGKRA EFVAGWTYWA CWLTLAMADL TATGIYLRYW FPWLPQWVGP LAIIVLLLLI
NTVNVGLFGE LESWFSMIKV IAIVALSITG AVMIVLHTPV KGGNVSLTNL VNHGGFFPTG
WWGFLLSFQM VVFAFVGVEI VGQTASETAN PEQDIPKAIN TLPVRIGLFY VGSMLAIMSV
YPWNEIKTTS SPFVQVFMGI GVTAAAGILN FVVLTAAMSA TNSAIFSTSR SLYSLARNGH
APKKLSSLTK KAIPLNALTT SSLILFVVVI LNYVMPASIF AVVSTVSTIC FVIVWLMIMW
AHIVYRNQNK ASLGKFRMPG YPVTSWVTII FYLAVLALLF FIPTTQLALI ISILFVVVLA
ISYSFVRKA
//
