ID A0A0R1PAS5_9LACO Unreviewed; 662 AA.
AC A0A0R1PAS5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Peptidoglycan hydrolase {ECO:0000256|ARBA:ARBA00032108};
GN ORFNames=FD27_GL000489 {ECO:0000313|EMBL:KRL27748.1};
OS Limosilactobacillus frumenti DSM 13145.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Limosilactobacillus.
OX NCBI_TaxID=1423746 {ECO:0000313|EMBL:KRL27748.1, ECO:0000313|Proteomes:UP000051445};
RN [1] {ECO:0000313|EMBL:KRL27748.1, ECO:0000313|Proteomes:UP000051445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13145 {ECO:0000313|EMBL:KRL27748.1,
RC ECO:0000313|Proteomes:UP000051445};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 73 family.
CC {ECO:0000256|ARBA:ARBA00010266}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRL27748.1}.
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DR EMBL; AZER01000014; KRL27748.1; -; Genomic_DNA.
DR RefSeq; WP_057749640.1; NZ_AZER01000014.1.
DR AlphaFoldDB; A0A0R1PAS5; -.
DR STRING; 1423746.FD27_GL000489; -.
DR PATRIC; fig|1423746.3.peg.496; -.
DR OrthoDB; 37530at2; -.
DR Proteomes; UP000051445; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0004040; F:amidase activity; IEA:InterPro.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR CDD; cd00118; LysM; 5.
DR Gene3D; 1.10.530.10; -; 1.
DR Gene3D; 3.10.350.10; LysM domain; 5.
DR InterPro; IPR022263; KxYKxGKxW.
DR InterPro; IPR018392; LysM_dom.
DR InterPro; IPR036779; LysM_dom_sf.
DR InterPro; IPR002901; MGlyc_endo_b_GlcNAc-like_dom.
DR NCBIfam; TIGR03715; KxYKxGKxW; 1.
DR PANTHER; PTHR33734:SF35; LYSM DOMAIN-CONTAINING GPI-ANCHORED PROTEIN 1; 1.
DR PANTHER; PTHR33734; LYSM DOMAIN-CONTAINING GPI-ANCHORED PROTEIN 2; 1.
DR Pfam; PF01832; Glucosaminidase; 1.
DR Pfam; PF19258; KxYKxGKxW_sig; 1.
DR Pfam; PF01476; LysM; 5.
DR PRINTS; PR01002; FLGFLGJ.
DR SMART; SM00257; LysM; 5.
DR SMART; SM00047; LYZ2; 1.
DR SUPFAM; SSF54106; LysM domain; 5.
DR PROSITE; PS51782; LYSM; 5.
PE 3: Inferred from homology;
KW Antimicrobial {ECO:0000256|ARBA:ARBA00022529};
KW Bacteriolytic enzyme {ECO:0000256|ARBA:ARBA00022638};
KW Hydrolase {ECO:0000313|EMBL:KRL27748.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051445};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..41
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 42..662
FT /note="Peptidoglycan hydrolase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006408891"
FT DOMAIN 352..396
FT /note="LysM"
FT /evidence="ECO:0000259|PROSITE:PS51782"
FT DOMAIN 420..464
FT /note="LysM"
FT /evidence="ECO:0000259|PROSITE:PS51782"
FT DOMAIN 488..532
FT /note="LysM"
FT /evidence="ECO:0000259|PROSITE:PS51782"
FT DOMAIN 556..600
FT /note="LysM"
FT /evidence="ECO:0000259|PROSITE:PS51782"
FT DOMAIN 618..662
FT /note="LysM"
FT /evidence="ECO:0000259|PROSITE:PS51782"
FT REGION 43..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 400..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..83
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 662 AA; 69677 MW; E2430E6F4B5F4310 CRC64;
MRQSFTDSKT HYKMYKSGRK WMFAGLTAVS LIGATGVVAH ADEQTPTTPA EETTQSGANN
NKNQSSNAAS STASSSANSN VNSSAVASDS TSAVSAASQV IASANVASSA TSAASSATHQ
LEVTSDSKQN TLVVKPTAKA TATTTAAFAA QKTAAPQVNL NSLHFSNNAH SQQFIESVAP
GAINGWNKYG VLPSITVAQA ILESGWGRSS LSTQAHNLFG IKGSYNGRSV TMRTREVYGG
RSVYINDAFR AYANNSESVE DHGNFLYVNS RYHNLLGDTN YASVARKLRA DGYATDPNYA
NALIRLVQTY GLNQLDSVAF SGKTITNKGG NNDSSYSQSS SYGNNGNISG TGYYTVQSGD
TLSGIANRFS TNVNTLAHLN DIQNVNRIYV GQHLLVRQAS SNASTSRPSA PVTNNTQASG
TYTVQSGDTL SGIASRFGTS YETLAHLNNI ANPNLIHVGQ TLRLSGSSSS TTTNATSHTT
SSTSSAAGSY TVQSGDTLSA IAARYGMSWE TLARLNNISN PNVIMVGQVL RLSAGPTTHV
TVHNASRQVT SSSNGGQYVV QSGDTLSTIA ARYGMSYETL ARLNNISNPN MIMVGQRLNV
NGVATHSYRT TNHASYGNAY TVQSGDTLSA IAARYGLSWR SLAVKNGISN PNEIMVGQRI
VL
//
