ID A0A0R1RMW1_9LACO Unreviewed; 877 AA.
AC A0A0R1RMW1;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:KRL58592.1};
GN ORFNames=FC69_GL000244 {ECO:0000313|EMBL:KRL58592.1};
OS Latilactobacillus fuchuensis DSM 14340 = JCM 11249.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Latilactobacillus.
OX NCBI_TaxID=1423747 {ECO:0000313|EMBL:KRL58592.1, ECO:0000313|Proteomes:UP000051264};
RN [1] {ECO:0000313|EMBL:KRL58592.1, ECO:0000313|Proteomes:UP000051264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14340 {ECO:0000313|EMBL:KRL58592.1,
RC ECO:0000313|Proteomes:UP000051264};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRL58592.1}.
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DR EMBL; AZEX01000068; KRL58592.1; -; Genomic_DNA.
DR RefSeq; WP_056950730.1; NZ_AZEX01000068.1.
DR AlphaFoldDB; A0A0R1RMW1; -.
DR STRING; 1423747.FC69_GL000244; -.
DR PATRIC; fig|1423747.3.peg.251; -.
DR eggNOG; COG0383; Bacteria.
DR OrthoDB; 9764050at2; -.
DR Proteomes; UP000051264; Unassembled WGS sequence.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10815; GH38N_AMII_EcMngB_like; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF2; MANNOSYLGLYCERATE HYDROLASE; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 268..346
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 877 AA; 98647 MW; 6853831D49BF08DD CRC64;
MTKIHAIAHT HWDFEWYFTR QEARVQFAFH MDDVFAALTD NQLDYYLLDG QLSIIDDYLT
AFPEKESVLR QFVTAGRLFI GPWYTQIDEM VTSGESIVRN LKLGMRLGDA LGGVMKVGYL
PDSFGQGQDM PKIYNGVGIN STVFWRGFPS DNDARYFYWD SNDGSQVIAA NIKNGYYAGV
DLIEKDDVPA LLTRIATHTT ATNQVLPVGG DQRAIDFNLK TRLNQANDAI DTNDSIIESN
YPAFFDALAQ ETNLPAFSGE FIDPSDSKIH RGIYSSRYDL KQLYDQLERE MTYQIEPLMA
LAAHQGIESK QGLIDEIWQT IARGQAHDSS GGCNSDKTNQ DIYQRGVTAH QLAYSLKDYL
LRKLSISINN DQPIDLFAWN PLPMAINEVR ELTVSTKTAH FNVCDLTGQL VAFEVLSQEQ
ENAATLRRNP AEMTDDYYYV TKIALQTKIG ATDWCGYQLQ PTSTATMPVL KTTDTIDNRF
YAISATDGQL ELLVKATNQR YDNFLTLEDG GDEGDTYDFS PAFTDWLLTL DFTQADHSHF
EQGQLISRLR LNGTWQLPAN LAERQQQLRS GQVAYQLELV LKQDSESIGF NLTLDNQVLD
HRMRLVLHTG IQATDSFADT PFGTIQRPVE DPHLKDWQAI GYHEEPTSMR PMIHFANTHN
QEISWSFLTN GMKDFQLIGD QFDQLAITLF RGVGYLGRPD LKRRPSDASG LQTKVVATPD
SQLTGQLTFG GALVVTPDFQ PTALQQAHLL LSQSDLAYQN QTINRFTTPL QYFMMNPTAT
AIKHAPILAV NDLQVTFSSF MQTIDGTGFE LRLYNPTDQA ITLPGSLELH QNCRIAELDL
RGQVQATLAT SPSDYDLTTF GPGEIRTYGI YPIQPRA
//
