ID A0A0R1S4J6_9LACO Unreviewed; 384 AA.
AC A0A0R1S4J6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Cysteine desulfurase NifS {ECO:0000313|EMBL:KRL63454.1};
GN ORFNames=FC23_GL000695 {ECO:0000313|EMBL:KRL63454.1};
OS Lactobacillus psittaci DSM 15354.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=1122152 {ECO:0000313|EMBL:KRL63454.1, ECO:0000313|Proteomes:UP000051931};
RN [1] {ECO:0000313|EMBL:KRL63454.1, ECO:0000313|Proteomes:UP000051931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15354 {ECO:0000313|EMBL:KRL63454.1,
RC ECO:0000313|Proteomes:UP000051931};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU004504};
CC -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC aminotransferase family. NifS/IscS subfamily.
CC {ECO:0000256|ARBA:ARBA00006490}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRL63454.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AZFB01000003; KRL63454.1; -; Genomic_DNA.
DR RefSeq; WP_027825436.1; NZ_KE384473.1.
DR AlphaFoldDB; A0A0R1S4J6; -.
DR STRING; 1122152.GCA_000425905_00131; -.
DR PATRIC; fig|1122152.4.peg.708; -.
DR eggNOG; COG1104; Bacteria.
DR OrthoDB; 9808002at2; -.
DR Proteomes; UP000051931; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.260.50; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR020578; Aminotrans_V_PyrdxlP_BS.
DR InterPro; IPR016454; Cysteine_dSase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11601:SF50; CYSTEINE DESULFURASE ISCS 2-RELATED; 1.
DR PANTHER; PTHR11601; CYSTEINE DESULFURYLASE FAMILY MEMBER; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR PIRSF; PIRSF005572; NifS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00595; AA_TRANSFER_CLASS_5; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000051931}.
FT DOMAIN 2..366
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 384 AA; 42533 MW; 5B83E9F6D33A2DEA CRC64;
MIYFDNSATT KIYPDVLETY NKVSEEIWAN PSSLHKLGDR AHQLLEASRK QIADILGVQS
HEIFFTSGGS ESNNLAIKEA AWSKKEFGRH LITTSVEHAS VRNAFKHLEA RGFRVTYLPV
DEEGRINPND LKKALDSDTT LVSIMGVNNE IGTIQPIQAV SKILEAYPNI VFHVDNVQAF
GKDIWQQVFT DRVDLMSLSA HKYHAPRGVG ILFKKSGKML EPLIDGGGQE KGLRSGTENL
PAIAATAKAM RLVHEKESIN YQKESAIKQK IIDYLKDKPG ITIFSPMQAD FAPHVLTFSL
LGIRGETLVH TLESKGIYVS TTSACASKTS DEASTLASMK VDEKVATSAI RLSFDASNSL
AEADEFIDVF DKIYHHFAKV NHLK
//
