ID A0A0R1U118_9LACO Unreviewed; 764 AA.
AC A0A0R1U118;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=ATP-dependent DNA helicase {ECO:0000313|EMBL:KRL86180.1};
GN ORFNames=FC32_GL001891 {ECO:0000313|EMBL:KRL86180.1};
OS Ligilactobacillus apodemi DSM 16634 = JCM 16172.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=1423724 {ECO:0000313|EMBL:KRL86180.1, ECO:0000313|Proteomes:UP000051324};
RN [1] {ECO:0000313|EMBL:KRL86180.1, ECO:0000313|Proteomes:UP000051324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16634 {ECO:0000313|EMBL:KRL86180.1,
RC ECO:0000313|Proteomes:UP000051324};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRL86180.1}.
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DR EMBL; AZFT01000030; KRL86180.1; -; Genomic_DNA.
DR RefSeq; WP_025087348.1; NZ_BAMM01000010.1.
DR AlphaFoldDB; A0A0R1U118; -.
DR STRING; 1423724.FC32_GL001891; -.
DR PATRIC; fig|1423724.4.peg.1975; -.
DR eggNOG; COG3973; Bacteria.
DR OrthoDB; 9787585at2; -.
DR Proteomes; UP000051324; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR048228; HelD_bacillota.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR NCBIfam; NF041464; HelD_BACSU; 1.
DR PANTHER; PTHR11070:SF17; DNA HELICASE IV; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000051324}.
FT DOMAIN 207..599
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT COILED 65..92
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 228..235
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 764 AA; 88041 MW; 98D8257F0FED6917 CRC64;
MESIKQTEQK RMDHVVSQIK QAEKKAQKNI ATAKSDTKAI QDDFKNNLRI KTGTYSGMME
TALTVRQQQQ QLAERENNRT QAAKRLDVLE KMEKKPYFAR VDIKEQGEKQ EKIYIGLASF
SDEKDKFLVY DWRAPISSVY YDGGLGKVKY NTPVGEREVE LELKRQFMVE DGQIVTLFDT
DETVGDQMLL EVLDEGSDTK MKSIVTTIQK EQNKIIRDTD SELLFVQGAA GSGKTSAVLQ
RVAFLLYRYR GKLNSGQVVL FSPNQLFNDY IDQVLPELGE QNMVQMTYPQ FTNRRLPKLR
VETLQERFEE ENSGINKKIK ALKDSLKFFK ATTAYSNYLE KKGMRFKNIM HDGEVFFSKK
AIRDIYYSFN ENYHLGNRLF ATKEALIKRL NSKVGQAAKT DEVQKAVQGL SQQQLNALYG
DEPRNFENGD KELNFLARQY VMQDYKKIQT AILRNRFLNI NAQYVHFLRS VPELLDLSEF
DLTKEEWEQG IDQTIKLLKE RRLSLTDVTP YLYLYDRITG KKGDREIKQV FIDEIQDYTA
YQLAYLKTEF PRAKFTMLGD LNQAIFTKEN SHTLLNELST MFPKEKTKVV QLTTSYRSTQ
QITDFTKEVL VNGEKVTAFA RNGAKPTVIV DQDQAALVDD VVEILAKNDK AKKTTAIIGK
SLAECEALFE QLQKKGVATT LIRTENQRLV PGTLIVPSYL AKGLEFDAVI MWNANKQNYH
DESERQLVYT ICSRAMHQLD ILAAKELSPL FDTVDKNLYT LIKR
//
